NIHR using systematic reviews to inform funding

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Description: NIHR using systematic reviews to inform funding decisions Matt Westmore, Director of Finance and Strategy Sheetal Bhurke, Research Fellow NIHR Evaluation, Trials and Studies Coordinating Centre Funding Acknowledgement: This work was funded

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slide1. NIHR using systematic reviews to inform funding decisions Matt Westmore, Director of Finance and Strategy
Sheetal Bhurke, Research Fellow

NIHR Evaluation, Trials and Studies Coordinating Centre<br>
slide2. Funding Acknowledgement: This work was funded by the NIHR Evaluation, Trials and Studies Coordinating Centre
Department of Health Disclaimer: The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the NIHR, NHS or the Department of Health.

Emerging findings
The results presented here are still subject to peer review and so should be considered emerging findings<br>
slide3. Summary
NIHR is a major funder of applied health research

New primary research will only be funded if it is based on a review of existing evidence

Reviews are used to support the research question and define methodology

70-75% of funded trials explicitly referenced a review in their applications as justification for the research question

100% of funded trials that could, referenced a review to inform the research question and/or design<br>
slide5. 85% of Health Research Funding is wasted avoidably<br>
slide6. Adding Value in Research Framework Google “NIHR adding value in research framework”<br>
slide8. What do we mean by a systematic review

New primary research will only be funded if it is based on a review of existing evidence that is credible to your peers and:

Is completed according to a predetermined methodology
Methodology is adequately described to allow, in principle, replication by others
Has well defined and justified inclusion and exclusion criteria
Minimises bias and random error in a way proportionate to the risk of an inappropriate funding decision
Maximises completeness in a way proportionate to the risk of an inappropriate funding decision
References ongoing studies
Critically appraises for quality and relevance
Synthesises<br>
slide9. Who does what?
If it is a commissioned call – we have done it so applicant does not have to.

If not applicant does it
If a published review exists – use it adding in any more recent studies
If a published review does not exist review the evidence systematically
We check<br>
slide10. Bhurke et al “Are Health Technology Assessment (HTA) funded trials using systematic reviews to inform their design? A retrospective cohort” EMERGING FINDINGS – SUBJECT TO PEER REVIEW<br>
slide11. EMERGING FINDINGS – SUBJECT TO PEER REVIEW<br>
slide12. Summary
NIHR is a major funder of applied health research

New primary research will only be funded if it is based on a review of existing evidence

Reviews are used to support the research question and define methodology

70-75% of funded trials explicitly referenced a review in their applications as justification for the research question

100% of funded trials that could, referenced a review to inform the research question and/or design Thank you<br>