PPT-Counting Viruses Measuring the Latent HIV-1 Reservoir

Michael Hudgens UNC CFAR UNC Department of Biostatistics UNC CFAR Ron Swanstrom Collaboratory of AIDS Researchers for Eradication David Margolis Ilana Trumble Andrew Allmon. All rights reserved This tip sheet was developed in conjunction with the Great Trays TM Partnership dap with permission by ina Ba no inda Die an and sk ey from hn al ta tool art of Io old tar le nu at in 20 Io Nu trition Proj Io De ar me of Edu atio Daniel . Oberski. Dept. of Methodology & Statistics . Tilburg University, The Netherlands. (with material from Margot . Sijssens-Bennink. & . Jeroen. . Vermunt. ). About Tilburg University Methodology & Statistics. be cleared by CTL . ?. Una O’. Doherty. June 29, 2013. Infect (X4 or R5 HIV). Culture 3-4d. Measure total & integrated HIV DNA. Our experimental system. O. ’. Doherty U . J. Virol.. 2000. O. HIV Cure Research Training Curriculum. Scientific Leads. : Janet Siliciano. , PhD and . Robert Siliciano, . MDPhD. ,. Johns Hopkins School of Medicine. Community Leads. : Jeffrey Taylor, CARE; . Nasra. Nicolas . Chomont. , University of Montreal. Richard Jefferys, Treatment Action Group. The HIV CURE training curriculum is a collaborative project aimed at making HIV cure research science accessible to the community and the HIV research field. . UZ-UCSF ANNUAL RESEARCH DAY. 05 MAY 2017. W. Samaneka. MBChB. , MSc. For ACTG Team. Background. Current . evidence suggests that . ART instituted early during acute HIV infection (AHI) is key to containing HIV reservoir establishment . gnidimacrin. alone and in combination with an HDAC inhibitor. Li Huang. Duke University, North Carolina, . USA. Towards . an HIV . cure. Latent . HIV . reservoirs. “Shock . and . kill” strategy. John Thornhill. Sanctuary. Sites. Barriers . to . HIV cure: . Tissue reservoirs. HIV infects CD4 cells. Some become resting cells; ‘reservoir’. Created from Coiras M, et al. Nat Med 2009;7:798–812. . VOCABULARY. Virus. Capsid. Envelope. Human . Immunodeficiency Virus (HIV. ). Influenza. Lytic Cycle. Lysogenic Cycle. Lysis. Retrovirus. Prerequisite questions. What are the eight characteristics which all living things have in common. HIV1 and slower to progress to AIDS.. Most cases are due to type1.. Modes of transmission. 1-sexual.. 2- perinatal.. 3-parenteral(occupational and intravenous drug injection).. 4- blood transfusion.. Professor of Medicine. The Johns Hopkins University School of Medicine. Baltimore, Maryland. Update . on HIV Cure . Research. FORMATTED: 11/17/15. New Orleans, Louisiana: December 15-17, 2015. Slow decay of the reservoir. As a group discuss for 1 minute. Be able to defend your answer for the class!. Are . VIRUSES. alive?. Growth and Development. Reproduce. Change Over Time. Obtain and Use Energy. Maintain Homeostasis. UZ-UCSF ANNUAL RESEARCH DAY. 05 MAY 2017. W. Samaneka. MBChB. , MSc. For ACTG Team. Background. Current . evidence suggests that . ART instituted early during acute HIV infection (AHI) is key to containing HIV reservoir establishment . John Thornhill. Imperial College London. No disclosures to declare. Follicular CD8. +. T-cells (fCD8) in GALT are associated with lower HIV-1 reservoir in the terminal ileum after ART initiated during PHI.