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ALL, Acute lymphoblastic leukemia; ALL, Acute lymphoblastic leukemia;

ALL, Acute lymphoblastic leukemia; - PowerPoint Presentation

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Uploaded On 2022-08-01

ALL, Acute lymphoblastic leukemia; - PPT Presentation

BCMA Bcell maturation antigen DLBCL diffuse large Bcell lymphoma DLL3 deltalike ligand 3 GPC3 Glypican3 HCC hepatocellular carcinoma HIV human immunodeficiency virus IIT investigatorinitiated trial NHL nonHodgkin lymphomas MM multiple myeloma NSCLC non small cell lung canc ID: 931867

cell cartitude bcma phase cartitude cell phase bcma lung gpc3 iit multiple johnson hiv nsclc small hcc claudin nhl

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Slide1

ALL, Acute lymphoblastic leukemia; BCMA, B-cell maturation antigen; DLBCL, diffuse large B-cell lymphoma; DLL3, delta-like ligand 3; GPC3, Glypican-3; HCC, hepatocellular carcinoma; HIV, human immunodeficiency virus; IIT, investigator-initiated trial; NHL, non-Hodgkin lymphomas; MM, multiple myeloma; NSCLC, non small cell lung cancer; SCLC, small cell lung cancer; TCL, T-cell lymphoma*In collaboration with Janssen, Pharmaceutical Companies of Johnson & Johnson. †Phase 1 IIT in China. ‡Multiple allogeneic platforms are being developed.

Infectious Diseases

SolidTumors

TCL†(CD4)

NHL-DLBCL/ALL(CD19 x CD20 x CD22)

MM*(BCMA)

HIV (Undisclosed)

LEGEND-2†

CARTITUDE-4

Gastric†(Claudin 18.2)

Hematologic Malignancies

CARTIFAN-1

CARTITUDE-2

Global

China

US

HCC, NSCLC (GPC3)

SCLC (DLL3)

CARTITUDE-1

Pancreatic

(Claudin 18.2)

MM (BCMA)

Autologous

CARTITUDE-5

Allogeneic

Preclinical

Phase 1

Phase 2

Phase 3

CARTITUDE-6

Autologous