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Zachary Morris MDPhD Assistant Prof Dept of Human Oncology September 11 2019 gt70 of breast cancers are ER Growth of 2540 is resistant to antiestrogens Metastatic ER cancers account for most breast . one receptor ER = estrogen receptor; ERK1/2 = extracellular signal-regulated kinase-1/2; GH = growth hormone; IGF = insulin-like growth factor; MAPK = mitogen-activated protein kinase; MNU = -methyl-- Diagnostic MGM. Breast US – cystic or solid ; does not show . microcalcifications. !!!. Breast MRI - younger . pts. with very dense breasts. Percutaneous . Bx. FNAB - cytology. Needle core . bx. Image guided vs non image guided. Lesions of female breast are much more common than lesions of male breast. Most of these lesions are benign. Breast cancer is . 1. st. most common cancer. ; and . 2. nd. most common cause of cancer deaths in women. Myth . vs. Fact. What you really need to know. Mark D Filidei, D.O.. Director of Integrative Medicine. Amen Clinics. The two main principles of Bio-identical Hormone Therapy . (. BHRT):. 1) Use of natural (human bio-identical) hormones: exactly like those produced in the body. for EARLY-STAGE BREAST CANCER. Dr. Maria C.E. Jacobs. Director, Radiation Oncology. Mercy Medical Center. Baltimore, Maryland. EARLY-STAGE BREAST: . . Local Breast Treatment. BCT consisting of conservative surgery (CS) with lumpectomy/partial mastectomy and RT. Survivorship. Mary Helen Hackney, M.D., FACP. VCU Massey Cancer Center. March 2013. I have no disclosures . I am employed by VCU. 2008 Estimated US Cancer Deaths*. ONS=Other nervous system.. Source: American Cancer Society, 2008.. Targeting endocrine-resistance pathways in breast cancer Clara Natoli, Chieti Endocrine responsive breast cancer Luminal A High expression of ER & ER-related genes Lower Julie R. Gralow, M.D.. Director, Breast Medical Oncology. Jill Bennett Endowed Professor of Breast Cancer. Professor, Global Health. University of Washington School of Medicine. Fred Hutchinson Cancer Research Center. 4Box 4Alternatives to Hormone Therapy To Help Preventostmenopausal Conditions and Relieve Menopausal SymptomsMenopause may cause otherchanges that produce no symp-toms yet affect your healthForinstanc RISK FACTORS FOR BREAST CANCER. Family . Hx. .: first- . and second-degree relatives with breast cancer and their age at diagnosis. .. RISK FACTORS FOR BREAST . CANCER . (. cont.). . Hormonal . Risk Factors. Rajiv Doddamani. . PGY – 3, Internal Medicine . . St. Joseph Mercy Ann Arbor . Learning objectives . Explain the principles of breast cancer screenings . Breast Cancer in the US . Breast Cancer is estimated to affect . over 230,000 . women . annually in the US. Based on SEER Database rates from 2009-2011, the . cumulative lifetime risk. of an average woman in the general US population is 12.3%. . Breast Cancer | . Epidemiology- Australia. Australian Institute of Health and Welfare 2014. ACIM (Australian Cancer Incidence and Mortality) Books. Canberra. AIHW. Overall is the third leading cause of cancer. ishtiaq. . FCPS R3 general surgery unit one UKSO . prof . tariq. . ghaffor. . sb. . . Objectives. Surgical Anatomy. Investigations. Diagnosis.