PPT-Using Biomarkers in developing Precision Medicine in Idiopathic Nephrotic Syndrome

Omar Ragy Patrick Hamilton Shelley Harris Sandip Mitra Kay Poulton Manchester Royal Infirmary Department of Renal Medicine Acknowledgment Introduction Idiopathic Nephrotic syndrome. /nephritic syndrome. Hrishi Narayanan. Learning Outcomes. Understand the key differences between . nephrotic. and nephritic syndrome (nephritis). Describe initial investigations and management of . nephrotic. IMRE NOTH, MD. CLINICAL CARE: NEW AND EVOLVING TREATMENT STRATEGIES . NOVEMBER 14, 2015. What is “Precision” Medicine?. Precision medicine. is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person.. Hrishi Narayanan. Learning Outcomes. Understand the key differences between . nephrotic. and nephritic syndrome (nephritis). Describe initial investigations and management of . nephrotic. and nephritic syndrome (nephritis). Rodney D Gilbert. Patient JM. 14 year old girl, presented 06/07/2015. Severe oedema, . hypoalbuminaemia. and proteinuria. Diagnosis nephrotic syndrome. No response to steroids. At Southampton. Cushingoid. Dr. . Kriti. . mohan. Assistant Professor, Pediatrics. Learning objectives. Definition of . Nephrotic. syndrome. Etiopathogenesis. of . nephrotic. syndrome. Clinical manifestation. Evaluation. Management. nephrotic syndrome in Honduras, 2016-2020. HYPOTHESIS. : . P. erform clinic. op. athological correlation and identify the most frequent histological lesions in the pediatric population with idiopathic nephrotic syndrome. ANITA TSADO. MIRACLE OGBONNA. BRIDGET EBIRERI. Nephritic syndrome. Nephrotic syndrome. Types of glomerulonephritis. Treatment. CONTENTS. Nephritic Syndrome. Nephritic syndrome—due to GBM disruption. Inflammation of the glomerulus.. ValueAwareness,Testing & Educate stakeholders on the value including physicians, pathologists, payers, patient Develop EU and UK-wide guidelines to promote the use of comprehensive testing at various ABSTRACTGreat advances have been made in the pathophysiologic and therapeutic areas of membranous nephropathy in the last years. The description of autoantibodies directed against phospholipase A2 rec 1 Background: Nephrotic syndrome is one of the most common renal diseases in children. Nephrotic syndrome is the clinical manifestation *Correspondence to: Md. Mozammel Haque, Junior Consultant, Depa 45 17, 20089 (7.3%) each. Among 231 patients, 158 (68.4%)proliferative GN in 2 each. (77%), Srivastava, et al (76%)(1-4). A higher incidence ofThis high incidence of bacterial peritonitis may be AA Karen L. Edwards, . PhD. Professor, Dept. of Epidemiology. School of Medicine. University of . California, Irvine. Irvine, CA. Outline. Two National Initiatives . Precision Medicine Initiative . Cancer .  . DIAGNOSIS. History .. Physical exam.. Investigations:. Labs.. Imaging.. Renal biopsy.. History . Onset ( sudden or gradual).. Symptoms: . edema,hematuria,proteinuria,etc. .. Family history.. Drug history.. Biochemistry. qxsang@chem.fsu.edu. Biochemical, Molecular, and Pathological Mechanisms of Cancer, Stroke, Obesity, and Stem Cell Differentiation, and Cancer Biomarker and Drug Discovery for Precision .