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Using Biomarkers in developing Precision Medicine in Idiopathic Nephrotic Syndrome Using Biomarkers in developing Precision Medicine in Idiopathic Nephrotic Syndrome

Using Biomarkers in developing Precision Medicine in Idiopathic Nephrotic Syndrome - PowerPoint Presentation

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Uploaded On 2022-08-03

Using Biomarkers in developing Precision Medicine in Idiopathic Nephrotic Syndrome - PPT Presentation

Omar Ragy Patrick Hamilton Shelley Harris Sandip Mitra Kay Poulton Manchester Royal Infirmary Department of Renal Medicine Acknowledgment Introduction Idiopathic Nephrotic syndrome ID: 934433

syndrome nephrotic introduction idiopathic nephrotic syndrome idiopathic introduction mcd fsgs patients medicine treatment covid vaccine

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Slide1

Using Biomarkers in developing Precision Medicine in Idiopathic Nephrotic Syndrome

Omar Ragy, Patrick Hamilton, Shelley Harris, Sandip Mitra,Kay Poulton

Manchester Royal InfirmaryDepartment of Renal Medicine

Slide2

Acknowledgment:

Slide3

Introduction:

Idiopathic Nephrotic syndrome

MCD

FSGS

Slide4

Introduction:

Idiopathic Nephrotic syndrome

MCD

FSGS

Slide5

Introduction:

Idiopathic Nephrotic syndrome

MCD

FSGS

Clinical picture of nephrotic syndrome

Slide6

Introduction:

Idiopathic Nephrotic syndrome

MCD

FSGS

Respond to treatment

Frequent relapses

Resistant to treatment

Slide7

Introduction:

Covid -19 vaccine Nephrotic syndrome

MCD

FSGS

Slide8

Aims and methods:

Idiopathic Nephrotic syndrome

Covid -19 vaccine Nephrotic syndrome

7 patients

Control cases

7 patients

7 patients

CD80

suPAR

Cytokine panel including IL10, IL15, IL2, IL4, IL5, IL6, TNF-alfa, sCD40L, MCP1, TIMP1-4

 Anti

nephrin

Antibodies

Blood and Urine samples were taken pre and post immunosuppression and will

be evaluated for :

Slide9

Thank you for your attention