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Ta SUP Table I items from Medical records Ta SUP Table I items from Medical records

Ta SUP Table I items from Medical records - PowerPoint Presentation

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Ta SUP Table I items from Medical records - PPT Presentation

  items from Blood Test Values items from CTimaging interpretation example anonymous ID WBC white blood cell count air trappingpLower lobe Bilateral lungs date of TEMPLATE entry RBC red blood cell count ID: 930523

stenosis lobe mir tgfb1 lobe stenosis tgfb1 mir lung member tnf chain binding left alpha moderate atp coa erythrocyte

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Slide1

Ta

SUP Table I

items from Medical records

 

items from Blood Test Values

items from CT-imaging interpretation, example

anonymous ID

WBC (white blood cell count)

air trapping:p:Lower lobe | Bilateral lungs

date of TEMPLATE entry

RBC (red blood cell count)

air trapping:n:Lower lobe | Bilateral lungs

gender

Hb (hemoglobin)

air trapping:s:Lower lobe | Bilateral lungs

age

Ht (hematocrit)

crazy-paving pattern:p:Lower lobe | Bilateral lungs | Dorsal

date of entry

MCV

crazy-paving pattern:n:Lower lobe | Bilateral lungs | Dorsal

The name of the updater

MCH

crazy-paving pattern:s:Lower lobe | Bilateral lungs | Dorsal

presence or absence of symptoms

MCHC

fluid:p:Lower lobe | Left lung

PS

RDW-SD

fluid:n:Lower lobe | Left lung

dyspnea on exertion

PLT (platelet count)

fluid:s:Lower lobe | Left lung

MRC(mMRC)

Neutrophils (analyser method)

mild stenosis, calc:p:5

coughing

Lymphocytes (analyser method)

mild stenosis, calc:n:5

Sputum

Monocytes (analyser method)

mild stenosis, calc:s:5

fever

Eosinophils (analyser method)

mild-moderate stenosis, calc:p:1

body weight

Basophils (analyser method)

mild-moderate stenosis, calc:n:1

weight loss

Neutrophil count

mild-moderate stenosis, calc:s:1

shortness of breath

reticulocyte

moderate stenosis:p:4PD

heartburn

erythrocyte morphology-codocyte

moderate stenosis:n:4PD

decreased appetite

erythrocyte morphology- haemagglutination

moderate stenosis:s:4PD

smoking history

erythrocyte morphology-poikilocyte

moderate-severe stenosis:p:Dx9

1 Cough

erythrocyte morphology-Howell-Jolly body

moderate-severe stenosis:n:Dx9

2 sputum

erythrocyte morphology-none

moderate-severe stenosis:s:Dx9

3 breathlessness

erythrocyte morphology-Leptocyte

pure GGN:p:S1|Left lung

4 Shortness of breath on exertion

erythrocyte morphology- anisocytosis

pure GGN:n:S1|Left lung

5 Daily life

erythrocyte morphology-Rouleaux formation

pure GGN:s:S1|Left lung

6 Confidence to go out

T (CD3)

pure GGO:p:S8|Lower lobe | Left lung

7 Sleep

B (CD19)

pure GGO:n:S8|Lower lobe | Left lung

8 Vitality

TH/I (CD4)

pure GGO:s:S8|Lower lobe | Left lung

Total CAT

TS/C (CD8)

reversed halo

sign:p:Lower

lobe | Inner | Right lung

Slide2

Ta

SUP Table II

ID

Symbol

Entrez Gene Name

P04217

A1BG

alpha-1-B glycoprotein

P01023

A2M

alpha-2-macroglobulin

A8K2U0

A2ML1

alpha-2-macroglobulin like 1

Q9NRG9

AAAS

aladin WD repeat nucleoporin

Q86V21-2

AACS

acetoacetyl-CoA synthetase

P49588

AARS1

alanyl-tRNA synthetase 1

O95342

ABCB11

ATP binding cassette subfamily B member 11

Q9NP58

ABCB6

ATP binding cassette subfamily B member 6 (Langereis blood group)

Q9NP78

ABCB9

ATP binding cassette subfamily B member 9

P33527

ABCC1

ATP binding cassette subfamily C member 1

O15439

ABCC4

ATP binding cassette subfamily C member 4

O15440

ABCC5

ATP binding cassette subfamily C member 5

Q9UNQ0

ABCG2

ATP binding cassette subfamily G member 2 (Junior blood group)

Q96IU4

ABHD14B

abhydrolase domain containing 14B

Q8IZP0

ABI1

abl interactor 1

Q9P2A4

ABI3

ABI family member 3

Q9P1F3

ABRACL

ABRA C-terminal like

P09110

ACAA1

acetyl-CoA acyltransferase 1

P49748

ACADVL

acyl-CoA dehydrogenase very long chain

P24752

ACAT1

acetyl-CoA acetyltransferase 1

Q9BWD1

ACAT2

acetyl-CoA acetyltransferase 2

P12821

ACE

angiotensin I converting enzyme

P22303

ACHE

acetylcholinesterase (Cartwright blood group)

Q9UKV3

ACIN1

apoptotic chromatin condensation inducer 1

P53396

ACLY

ATP citrate lyase

Q15067

ACOX1

acyl-CoA oxidase 1

P24666

ACP1

acid phosphatase 1

P11117

ACP2

acid phosphatase 2, lysosomal

P15309

ACP3

acid phosphatase 3

P33121

ACSL1

acyl-CoA synthetase long chain family member 1

O60488

ACSL4

acyl-CoA synthetase long chain family member 4

Slide3

 

SUP Table III

1

Annexin A7

ANXA7

I

9

CD40LG, IGF1, NR3C1, OPRM1, PTEN, SRC, VHL(von Hippel-Lindau tumor suppressor), VIM, miR19b-3p, opipod

2

Inter-alpha-trypsin inhibitor heavy chain 1

ITIH1

I

6

TGFb1, SPHK1, SLC6A4, PPARG, TNF, IL-10

Inter-alpha-trypsin inhibitor heavy chain 2

ITIH2

I

2

TNF, C3

Inter-alpha-trypsin inhibitor heavy chain 3

ITIH3

I

2

ADAM10, TGFb1

Inter-alpha-trypsin inhibitor heavy chain 4

ITIH4

I

1

ADAM10

Inter-alpha-trypsin inhibitor heavy chain 5

ITIH5

I

1

TGFb1

Inter-alpha-trypsin inhibitor heavy chain 6

ITIH6

I

1

miR125b-5p

3

28S ribosomal protein S17, mitochondrial

MRPS17

N

0

4

Agrin,

AGRN

I

6

TGFb1, SRC, VIM, CTNNB1, C3,

miR-184

5

Sorcin

SRI),

SRI

I

4

TGFb1, USHBP1, STAT3, miR142-5p

6

Polyunsaturated fatty acid lipoxygenase

ALOX12

I

5

TGFb1, PPARG, PLA2G4A, PDGFRA, SLC7A11

7

Peflin

PEF1

N

0

8

Purine nucleoside phosphorylase

PNP

I

2

TGFb1, miR-30c-5p

9

Four and a half LIM domains protein1

FHL1

I

3

TGFb1, SRC, CTNNB1

10

Protein-L-isoaspartate(D-aspartate) O-methyltransferase

PCMT1

I

3

AGTR1, VHL, PPARG

11

Type 2 phosphatidilinositol 4,5-bisphosphate 4-phosphatase

PIP4P2

I

1

TNF

12

Heme-binding protein 2

HEBP2

I

1

SHMT2

13

Calpain-1 catalytic subunit

CAPN1

I

11

TGFb1, TNF, miR125b-5p, imatinib, STAT3, VIM, VHL, PTEN, MRC2, CTNNB1, miR-140-5p

14

Plexin domain-containing protein 2

PLXDC2

I

2

IGF1, TNF

15

Tyrosine-protein phosphatase non-receptor type 6

PTPN6

I

31

TGFb1, CD44, IL10, DHFR, LYN, FLT3, SH2D1B, ABL1, LCK, FGFR2, FGFR1, TNF, N-acetyl-L-cysteine, IDO1, SFTPA1, CTNNB1, NFKB1, miR155, VIM, PTEN, MHCclassII, RET, SRC, STAT3, PDGFRA, PDGFRB, KDR, CSF1R, KIT, KLRD1, CD46

16

Tyrosine-protein kinase Lyn

LYN

D

30

IPF, nintedanib, miR30c-5p, let-7a-5p, miR-30, IL10, TNF, imatinib, PLAU, DSP, NFKB, STAT3, LCK, IGF1, SRC, SPHK1, FLT3, PDGFRA, MSR1, CD44, FGFR2, KIT, MHCclassII, CD40LG, FAS, CSF1R, CFLAR, C5AR1, CRLF2, C5, BCR-ABL1

17

Serine/threonine-protein kinase TAO3

TAOK3

I

1

miR17-5p

18

GTP-binding nuclear protein Ran

RAN

I

15

TNF, TERT, VHL, OPRM1, NR3C1, LCK, CTNNB1, ABL1, morphine, miR-17, miR-17-5p, miR-30, miR-142-3p, miR-197-3p, miR-140-5p

19

2’,3’-cyclic-nucleotide 3’-phosphodiesterase,

CNP

I

3

IGF1, TNF, NPPB

20

Macrophage migration inhibitory factor

MIF

I

19

TGFb1, bleomycin, VHL, STAT3, SRC, TNF, PLA2GA4, PRKAA, MMP1, MMP13, N-acetyl-L-cysteine, JGF1, IL10, IL25, FAS, CFLAR, C3AR1, CD44, CD40LG