PPT-Nucleotide Metabolism Pyrimidine

Met Purine Met Learning Objectives 1 How Are Purines Synthesized 2 How Are Purines Catabolized 3 How Are Pyrimidines Synthesized and Catabolized   4 How Are . DNA: Picture 51. http://info.bio.cmu.edu/courses/03231/ProtStruc/ProtStruc.htm. B-DNA: The advent of modeling. http://molvis.sdsc.edu/pdb/dna_b_form.pdb. 46 Å. . 12 base sequence. (1953-2003). DNA: Size, Shape & Self Assembly. OBJECTIVES:. Nomenclature of nucleic acids: . a. nucleosides*. . b. nucleotides. Structure . and function of . purines and pyrimidines. . Origin . of atoms in the purine . ring and in the pyrimidine ring.. nucleotides is essential for . life . processes. nucleotides . are the . activated precursors . of nucleic . acids. As such, they are necessary for the replication of the genome . an . adenine nucleotide, ATP, is . C483 Spring 2013. 1. A . ribose sugar is added to ________ rings after their synthesis and to ________ rings during their synthesis.. A) purine; pyrimidine. B) pyrimidine; purine. C) purine; purine. D) pyrimidine; pyrimidine. Slides. Nucleotide . Metabolism. nucleotide. nucleoside. a key molecule in purine and pyrimidine biosynthesis. fig 22-32. purines: where does all them darn atoms come from??. fig 22-33. fig 22-33. ETC.. De Novo. Synthesis of . Purine. Nucleotides. We use for . purine. nucleotides the entire . glycine. molecule (atoms 4, 5,7), the amino nitrogen of . aspartate. (atom 1), amide nitrogen of glutamine (atoms 3, 9), components of the . Metabolism. Dr. Anissa Atif Mirza. Synopsis. Fates of dietary Nucleoproteins/Nucleic Acids.. De novo Biosynthesis of Purines and Pyrimidines.. Salvage of Purines and Pyrimidines. Catabolism of Purines and Pyrimidines. OBJECTIVES:. Nomenclature of nucleic acids: . a. nucleosides*. . b. nucleotides. Structure . and function of . purines and pyrimidines. . Origin . of atoms in the purine . ring and in the pyrimidine ring.. Luke Chen, PhD. NCCU-01-16VW. December 27, 2016. Author: Doug Lee, PhD. Metabolomic impact of Nrf2 activation on esophageal epithelium. Study Overview. Study Design. Study Objective. The goal of this study was to characterize the metabolic impact of loss of Nrf2 and Keap1 on mouse esophageal epithelium tissue and (in a separate adult wild type cohort) to identify changes in esophageal epithelial . Dr. Anissa Atif Mirza. Synopsis. Fates of dietary Nucleoproteins/Nucleic Acids.. De novo Biosynthesis of Purines and Pyrimidines.. Salvage of Purines and Pyrimidines. Catabolism of Purines and Pyrimidines. Kumar. Nucleotide Metabolism. PURINE RIBONUCLEOTIDES: formed . de novo. i.e., purines are . not. initially synthesized as free bases. First purine derivative formed is Inosine Mono-phosphate (IMP). life . processes. nucleotides . are the . activated precursors . of nucleic . acids. As such, they are necessary for the replication of the genome . an . adenine nucleotide, ATP, is . the universal currency of energy. A guanine . The pathway consists of 6 enzymatic steps to form UMP. Unlike in . purine. biosynthesis. the . pyrimidine. ring is first formed and the the R5Pis added as PRPP. The N1,C4, 5 & 6 are all derived. Presented . by. Ms. . P. . . H. . Giri. Department of Microbiology. Deogiri . College, Aurangabad. B.Sc. F. Y.. Semester II. Paper No. V. Basic Biochemistry. Unit 4 Nucleic acids. Ms. . Priyanka. H. .