PPT-ANTIMICROBIAL DRUGS Introduction

A chemotherapeutic agent is a chemical that combats disease in the body An antimicrobial drug is a chemical substance that destroys diseasecausing microorganisms with minimal damage to host tissues. Easow Chiranjoy Mukhopadhyay PG Shivananda Department of Microbiology Manipal College of Medical Sciences Pokhara Nepal Received January 13 2005 Background objectives Shigellae play an important role as a causative organism of acute gastroenterit Environment and. Antimicrobial Chemotherapy. 1. 8 and 9. Copyright © McGraw-Hill Global Education Holdings, LLC. Permission required for reproduction or display.. 2. Definition of Frequently Used Terms. Steve Grapentine PharmD, BCPS. Antimicrobial Stewardship Program. grap0013@umn.edu. (612)813-8360 . A) 25%. B) 50%. C) 75%. D) 90%. What percentage of antimicrobial use in the average healthcare setting is appropriate?. What are antibiotics?. Definition: chemicals produced by one microorganism to kill or inhibit the growth of other microorganisms. Now included the semi-synthetic antibiotics. Effective against bacteria. Regulations. An Environment of Change. Brian Lubbers, DVM, PhD, . DACVCP. Director of Clinical Microbiology. Changing Regulations. Cephalosporin . Extralabel. Use Restriction. FDA Guidance 209. FDA Guidance 213. Antibiotics. Antimicrobial drugs naturally produced by microorganisms. Penicillium. . species: . Penicillins. Cephalosporium. . specis. : . cephalosporins. Streptomyces. . species:. . lincosamides. Mr. . Shadi. . ALashi. Antimicrobial control agents. Usually, microbial controls are used to avoid contamination of pure cultures, prevent infection, or treat existing diseases.. A . microbiocidal. Ph.D. Pharmacology & Therapeutics. College of Medicine/Al-. Nahrain. University. Principles of. Antimicrobial. Therapy. 4/10/2017. 1. Haitham Alwali. Antimicrobial therapy takes advantage of the biochemical differences . Therapy. The development of antimicrobial drugs represents one of the most important advances in therapeutics, both in the control or cure of serious infections and in the prevention and treatment of infectious complications of other therapeutic modalities such as cancer chemotherapy, immunosuppression, and surgery.. ……………………………………………………………………………………………………………………………………………………………………………………………………………………………………………. Dr. . Haider. Abdul-Lateef . Mousa. Learning Objectives. •To understand how antibiotics work. • To review how drug resistance develops in bacteria. • T o summarize current status of antimicrobial resistance in selected bacteria. Sulfanilamides. . . Derivatives. . of. . naphthyridine. . and. . quinolonecarboxylic. . acids. . . Derivatives. . of. 8-oxyquinoline, . quinoxaline. . and. . nitrofural. . . Characteristics. 1. Paul Ehrlich . developed . the concept of chemotherapy . to treat microbial diseases; he predicted the development of chemotherapeutic agents, which would kill pathogens without harming the host (. Antimicrobial drugs . have the ability to . injure or kill . an . invading microorganism without harming the cells of the host . (biochemical differences that exist between microorganisms and human). In most instances, this .