angleclosure glaucoma Jimmy T Le Benjamin Rouse Gus Gazzard Issue 6 2018 A presentation to Meeting name Date Table of Contents 01 Background 02 Types of studies 03 Key results 04 ID: 1036043
Download Presentation The PPT/PDF document "Iridotomy to slow progression of visual ..." is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
1. Iridotomy to slow progression of visual field loss in angle-closure glaucomaJimmy T Le, Benjamin Rouse, Gus GazzardIssue 6, 2018A presentation to:Meeting nameDate
2. Table of Contents01Background02Types of studies03Key results04Tables (Risk of Bias/Forest Plots)05Conclusions06Acknowledgements
3. 01: BackgroundPrimary angle-closure glaucoma is a type of glaucoma associated with a physically obstructed anterior chamber angle. Elevated IOP is associated with glaucomatous optic nerve damage and visual field loss.Laser peripheral iridotomy (often just called ‘iridotomy’) is a procedure to eliminate pupillary block by allowing aqueous humor to pass directly from the posterior to anterior chamber through use of a laser to create a hole in the iris. ObjectiveTo assess the effects of iridotomy compared with no iridotomy for primary angle-closure glaucoma, primary angle closure, and primary angle-closure suspects.
4. 02: Types of studiesParticipantsTwo randomized controlled trials (RCTs) with 1251 participants (2502 eyes) with bilateral asymptomatic primary angle-closure suspects.InterventionsNeodynium:yttrium-aluminium-garnet (Nd:YAG) laser iridotomy in one randomly selected eye.No iridotomy in the paired eye.
5. 03: Key results“At the time of this review, no data are available on the proportion of participants with progressive visual field loss at one year… [or] on the mean change in IOP at one year… [or] on gonioscopic findings at one year”“Neither the ANA-LIS nor the ZAP trial specified measuring need for additional surgery… [or] measuring number of medications to control IOP… [or] measuring change in BCVA… [or] measuring quality of life”
6. 04: Tables
7. 05: Conclusions“The available studies that directly compared iridotomy to no iridotomy have not yet published full trial reports.”“At present, we cannot draw reliable conclusions based on randomized controlled trials as to whether iridotomy slows progression of visual field loss at one year compared to no iridotomy.”
8. 06: AcknowledgementsCochrane Eyes and Vision US Satellite, funded by the National Eye Institute, National Institutes of HealthCochrane Eyes and Vision Editorial Base, funded by the UK National Health Service Research and Development ProgrammeJimmy T Le, Benjamin Rouse, Gus GazzardReview citationLe JT, Rouse B, Gazzard G. Iridotomy to slow progression of visual field loss in angle‐closure glaucoma. Cochrane Database of Systematic Reviews 2018, Issue 6. Art. No.: CD012270. DOI: 10.1002/14651858.CD012270.pub2.