PPT-Dolutegravir monotherapy

Dolutegravir monotherapy vs dolutegravir abacavir lamivudine for HIV1infected virologically suppressed patients results from the randomized non inferiority MONCAY trial L Hocqueloux. monotherapy. MONOI. MONET. PROTEA. DRV600. Design. Objective. Non inferiority in the proportion of patients with HIV-1 RNA < 50 c/. mL. at W48 (ITT analysis, missing/discontinuation/switch= failure, snapshot algorithm. vs. PI/r . monotherapy. Study PIVOT. Study MOBIDIP. LPV/r monotherapy (N = 82). Design. Randomisation. 1: 1. Open-label. Objective. Primary endpoint. : failure rate at W96 by ITT, defined as 1) a confirmed HIV . David Spach, MD. Clinical Director, Northwest AETC. Professor of Medicine, Division of Infectious Diseases. University of Washington. Last Updated: October 21, 2013. 2013 . Asilomar. Update. New Occupational . New pricing agreement will speed up access to generic, dolutegravir (DTG)-based fixed dose combinations (FDCs) . HIV positive people in low- and middle-income countries including South Africa can be treated for around R900 (US $75 a year) . HIV Drug Resistance (HIVDR) and Antimicrobial Resistance (AMR): Science and Action. IAS 2017 . Paris . 24. th. July 2017. Modelling the cost and cost-effectiveness of responses to . HIV drug resistance. of HIV. . Convenience, tolerability, simplicity. New & Investigational Agents. “Quad” Pill- . Stribild. Released by FDA 08-27-12. Tenofovir Emtricitabine Cobicistat Elvitegravir. “Booster”. This program will include a discussion of data that were presented in abstract form. . These data should be considered preliminary until published in a . peer-reviewed journal.. Immunotherapy in Gastrointestinal . PROTEA Trial. Darunavir/r . M. onotherapy. versus Triple Therapy . PROTEA. : Study Design. Source: . Antinori. A, et al. . J Int AIDS Soc. 2014;17:19525.. Darunavir 800 mg QD. + Ritonavir 100 mg . QD. SWORD-1 . and SWORD-. 2. Dolutegravir plus Rilpivirine as Maintenance Dual Therapy. SWORD-1 and SWORD-2: Design. Source: . Llibre. JM, et al. Lancet. 2018;39:839-49.. Background. : . Identical, randomized, multinational, open-label, industry-sponsored, parallel-group, . Dovato. ). Last Updated: November 28, 2022. Prepared by:. Brian R. Wood, MD. David H. Spach, MD. Dolutegravir-Lamivudine. Photograph courtesy of . ViiV. INSTI. NRTI. 50 mg. 300 mg. Dolutegravir-Lamivudine. FLAMINGO. Dolutegravir + 2 NRTIs versus Darunavir + RTV + 2 NRTIs . FLAMINGO: Study Design. Source: . Clotet. B, et al. . Lancet. 2014;383:2222-31. . Dolutegravir + . TDF-FTC or ABC-3TC. (n = 242). Darunavir + Ritonavir + . SPRING-2 Study. Dolutegravir. versus Raltegravir. SPRING-2: Design. Source: . Raffi. F, et al. Lancet. 2013;381:735-43.. Dolutegravir. : 50 mg QD. Fixed-dose NRTI backbone*. (n = 411). Raltegravir. Prepared by:. Brian R. Wood, MD. David H. Spach, MD. Last Updated: January 28, 2021. Dolutegravir (. Tivicay. ) . INSTI. Tivicay. . [TIV-eh-kay]. Dolutegravir. Treatment Naïve. : 50 mg once daily with or without food. Judith S. Currier, MD, MSc. Professor of Medicine. University of California Los Angeles. Financial Relationships With Ineligible Companies (Formerly Described as Commercial Interests by the ACCME) Within the Last 2 Years:.