TonicClonic Seizures in the Modern Era This program will include a discussion of offlabel treatment and investigational agents not approved by the FDA for use in the US 2017 ILAE Epilepsy Nomenclature ID: 637117
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Treatment of Generalized Tonic-Clonic Seizures in the Modern EraSlide2Slide3
This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the US.Slide4
2017 ILAE Epilepsy NomenclatureSlide5
Most Common IGE SyndromesSlide6
DRE at UK Epilepsy Referral ClinicsSlide7
Case 1Slide8
Case 1: Care by a General NeurologistSlide9
Case 1: Testing, Results, and DiagnosisSlide10
Importance of Referral Slide11
Apparent Drug Resistance in IGESlide12
Treatment Goals in IGESlide13
Expert Opinion Survey: DesignSlide14
Expert Opinion Survey: Treatment of IGE With GTCSFirst MonotherapySlide15
Expert Opinion Survey: Treatment of IGE With GTCSFirst Monotherapy (cont)Slide16
Expert Opinion Survey: Initial AED Selection* Slide17
Expert Review: AEDs of Choice Slide18
Perampanel: FDA Approved for GTCSSlide19
Other Drugs Used for the Treatment of GTCSSlide20
Case 2: General HistorySlide21
Case 2: Seizure HistorySlide22
Case 2: Findings and DiagnosisSlide23
Case 2: Treatment ConsiderationsSlide24
Case 2: Selecting AEDsSlide25
Case 2: Treatment OptionsFirst MonotherapySlide26
Case 2: Treatment OptionsFirst Monotherapy (cont)Slide27
Case 2: Treatment OptionsFirst Monotherapy (cont)Slide28
Case 2: Treatment OptionsFirst Monotherapy (cont)Slide29
Case 2: Treatment OptionsFirst Monotherapy (cont)Slide30
Case 2: Treatment Selection Slide31
North American AED Pregnancy RegistrySlide32
Basis of Uncontrolled Seizures With First-Line AEDSlide33
Case 3: HistorySlide34
Case 3: Selecting AED in DRESlide35
Treating DRE Slide36
ConclusionsSlide37
AbbreviationsSlide38
Abbreviations