PPT-MLAB 2401: Clinical Chemistry

Keri BrophyMartinez Designs in Instrumentation Electrochemistry Electrochemistry Basic principle Electrodes are used to selectively measure particular ions Instruments utilizing electrodes measure the potential difference charge that builds up at an interface when two different . Keri . Brophy. -Martinez. Methods of Glucose Measurement and Diabetic Management. Laboratory testing. Considerations. Reference values depend on: . . Type of specimen . . venous/capillary. Serum, plasma, whole blood. Keri . Brophy. -Martinez. Overview:. Amino Acids & Proteins. Amino Acids. Building blocks of proteins. Chemical properties determine biological activity. Origin. Majority made in the human. Generated from amino acid pool. Keri Brophy-Martinez. Measurement of . Enzymes & Their Clinical Significance. Measurement of Enzyme Activity. Often measured by catalytic activity then related to . concentration. Enzyme concentration is best measured by its activity or its rate of activity by observing:. Chemistry. Keri Brophy-Martinez. Point of Care Testing . 1. Point of Care Testing. Analytical patient - testing activities provided within the institution, but performed outside the physical facilities of the clinical laboratories. -Tobacco refusekg.30%- 2402CTOBACCOTOBACCO Cigars, cheroots and cigarillos, containing2402 10 10 ---Cigar and cherootsTu60%-2402 10 20 ---CigarillosTu60%- Cigarettes, containing tobacco :2402 20 10 -- Chemistry 1411. Fall 2012-2013. Ms. . Nida. . Jamil. Zakia. . AlAsaad. 201100622. Zainab. . AlHashim. 201001479. Ohood. . AlGuryafi. 200901235. Aminah. . AlRastem. 200800733. Chemistry has been aro. Keri Brophy-Martinez. Cardiovascular Conditions and Assessment. Functions of the Heart. Pumps blood to the organs of the body. Delivers oxygen and nutrients where they are needed. Removes waste products from tissues. Keri . Brophy. -Martinez. ABG Interpretation. Evaluating Acid-Base Disorders. ARMADA . acid-base balance made easy in 4 steps . 1. . A. . cidosis. or Alkalosis?. 2. . R. . espiratory. disorder?. • What is “Inorganic Chemistry”?. . - descriptor or professional subfield. . - same as “General Chemistry”?. • Highlights from the inorganic timeline. . - Lavoisier: origin of modern chemistry. Chapter 2. Molecular Representations. David Klein. Copyright © 2015 John Wiley & Sons, Inc. All rights reserved.. Klein, Organic Chemistry 2e . 2.1 Representing Molecules. There are many ways to represent molecules. The Fifth Edition of this classic text is revised and updated to incorporate the latest technologies, techniques, and opportunities in clinical chemistry. No other text is more careful to strike a balance between analytical principles and techniques and the correlation of laboratory results. This edition features additional case studies and questions, expanded coverage of endocrinology, and updated information on toxicology, geriatrics, and other topics.An Instructor\'s Resource Guide on CD-ROM includes chapter review questions and answers, teaching tips, an image bank, curriculum guidelines, and pedagogy by chapter. A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results. 1. Tietz, N.W., editor, Fundamentals of Clinical Chemistry, 3 Edition, W.B. Saunders Company, 1999. 2. Forrester, R.L., Walaji, L.J., Silvermann, D.A., and Pierre, K.J., Clin Chem., 22: 2, 1976. 3. CL Bridging the gap between the clinical laboratory and medical management by relating pathophysiology to analytical results in health and disease, this classic resource provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Its up-to-date, encyclopedic coverage of the field defines analytical criteria for the medical usefulness of laboratory procedures, introduces new approaches for establishing reference ranges, describes variables that affect tests and results, examines modern analytical tools and their impact on lab management and costs, and demonstrates the applications of statistical methods.All three editors are well known in the clinical chemistry world, and they bring a wealth of expertise to this reference.Encompasses the tremendous strides made in clinical laboratory medicine in recent years - keeping readers completely up to date.Nearly 800 tables and figures illustrate key issues in clinical chemistry.A comprehensive chapter containing tables of reference values provides one location for comparing and evaluating test results.A section has been added that contains 8 new chapters that focus on emerging issues and techniques in molecular diagnostics and genetics.Co-editor David Bruns, the editor of Clinical Chemistry, provides an authoritative look into laboratory medicine in general and specifically in the field of molecular technology.