PPT-WCN23-0887CLINICAL SIGNIFICANCE OF ANTI PHOSPHOLIPID ANTIBODIES IN LUPUS NEPHRITIS PATIENTS

DrHarish Sivagnanam Dr RamasubramanianV DrKannan BhabaV DrPKSenthil Kumar DrMurugesh Anand Tirunelveli Medical College and Hospital Tirunelveli BACKGROUND Systemic Lupus ErythematosusSLE is a common autoimmune disorder which involves multiple systems Even though its a common disorder of women in their reproductive age It can occur across all ages and genders Kidney is involved in almost 38 of the patients with SLE 40 to 60 of patients have overt findings at the time of diagnosis Patients with SLE can have antiphospholipid antibodies . Lupus Anticoagulant. General Approach of Haemostasis. Anti-. Phospholipids. antibodies.. Anti-. phospholipid. antibodies are a . heterogeneous. family of . autoantibodies. . that react with . epitopes. Prof. Hafiz . Ijaz. Ahmad. Department of Nephrology. Allama. . Iqbal. Medical College Lahore. Systemic Lupus . Erythematosus.  Systemic . Lupus . E. rythematosus. . (SLE) is a chronic inflammatory disease of unknown cause that can affect virtually any organ of the body. . The New Understanding: . Complexity and Promise. Jan L Hillson MD. Gold standard is agreement among specialists. To create the ACR criteria. Several specialists made lists of all the features seen in the patients they say have SLE. . Dr. : Mohamed . Abdelhafez. . . . . Nephrology specialist . . MNGH. Agenda. DEFINITION AND EPIDEMIOLOGY. ETIOLOGY AND PATHOGENESIS. RENAL AND EXTRARENAL MANIFESTATIONS. IMMUNOLOGIC TESTS IN LUPUS NEPHRITIS. - . Paraneoplastic. causes. Loulwah Mukharesh, Intern. Neurology Rotation (April 2012). Causes. Paraneoplastic. syndrome.  A. . heterogeneous group of neurologic disorders associated with systemic cancer and caused by mechanisms other than metastases, metabolic and nutritional deficits, infections, . Complementary and Alternative Medicine. Vitamins A, C, E and D. Cardiovascular disease in lupus. Benefits of certain diets, omega 3. Herbal Supplements. Disclaimer: No specific diet for the treatment of SLE exists at this time. Dr. Barbara Mendez . Assistant Professor at Albert Einstein . Director of the lupus Clinic . Systemic Lupus Erythematosus (SLE) . Introduction:. Lupus is a complex autoimmune disease. With excessive immune system activation. 10/03/19. Brian V Joachims, M.D.. Identify characteristics consistent with a diagnosis of Lupus. Interpret ANA results. Identify characteristics of Rheumatoid Arthritis. Describe . Spondyloarthropathy. . Challenges and Options . Grand . Rounds. Presented by:. Sumona Kabir, DO. January 21. st. , 2015 . Overview . Case presentation. Definition of SLE. Pathophysiology. Classification . Details of each classification. Presented by: Olivia Wassef What is Systemic Lupus Erythematosus (SLE)? • An Autoimmune Chronic Inflammatory Disease ▫ Immune System produces proteins called autoantibodies that turns against Autoimmune disease is a group of disorders in which tissue injury is caused by humeral (by auto-antibodies) or cells mediated immune response (by auto reactive T cells) to self antigens.. Normal, the immune system does not attach the self. However, there is a large . . Discussion and Conclusion. Reference. Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that primarily effects women with an 8:1 prevalence. Renal disease and gastrointestinal (GI) symptoms are very common presentations of lupus, seen in 50% of patients. Masri. It’s an . Inflammatory process . that involves . glomeruli. (. damage involving . the . basement . membrane. ,. capillary endothelium. , and . mesangium. ). . (while in . nephr. O. tic. syndrome the main structure to be damaged is . 32 European Review for Medical and Pharmacological Sciences2022; 26: 32-36 J. FREIRE DE CARVALHO1,2, T. LAROCCA SKARE 33 A search of articles published in the PubMed/MEDLINE, LILACS, and SciELO databa