PPT-WCN23-0887CLINICAL SIGNIFICANCE OF ANTI PHOSPHOLIPID ANTIBODIES IN LUPUS NEPHRITIS PATIENTS

DrHarish Sivagnanam Dr RamasubramanianV DrKannan BhabaV DrPKSenthil Kumar DrMurugesh Anand Tirunelveli Medical College and Hospital Tirunelveli BACKGROUND Systemic Lupus ErythematosusSLE is a common autoimmune disorder which involves multiple systems Even though its a common disorder of women in their reproductive age It can occur across all ages and genders Kidney is involved in almost 38 of the patients with SLE 40 to 60 of patients have overt findings at the time of diagnosis Patients with SLE can have antiphospholipid antibodies . Canis lupus . Canis lupus means a grey wolf with a brindled grey coat that lives in the northern regions in Latin. There are many more like the dire wolf or Canis dirus and the red wolf or Canis Rufus. . Lupus Anticoagulant. General Approach of Haemostasis. Anti-. Phospholipids. antibodies.. Anti-. phospholipid. antibodies are a . heterogeneous. family of . autoantibodies. . that react with . epitopes. Dr. Shauna O’Sullivan, DO, FACP. Assistant Professor of Medicine, USUHS. March 28, 2015. www.myquincy.net. Disclaimer. Nothing to disclose. The views and opinions expressed herein do not necessarily state or reflect those of the Naval Medical Center Portsmouth, DoD, or the United States . Prof. Hafiz . Ijaz. Ahmad. Department of Nephrology. Allama. . Iqbal. Medical College Lahore. Systemic Lupus . Erythematosus.  Systemic . Lupus . E. rythematosus. . (SLE) is a chronic inflammatory disease of unknown cause that can affect virtually any organ of the body. . The New Understanding: . Complexity and Promise. Jan L Hillson MD. Gold standard is agreement among specialists. To create the ACR criteria. Several specialists made lists of all the features seen in the patients they say have SLE. Christina McConnell, PGY-3. Which of the following is NOT one of the diagnostic criteria for lupus?. Biopsy proven lupus nephritis with a positive ANA. Hemolytic anemia. Psychosis. Single joint swelling. Jenny Hsu. Gene 210. 05-22-2012. Outline. Introduction. Symptoms. Pathogenesis. Who is at risk? . Associated . SNPs. Overview. rs10954213. Treatment. What is Lupus?. Autoimmune disease. immune responses intended for defense against invading microorganisms attack the body itself. LT James Prim, DO. LCDR Shauna O’Sullivan, DO. Naval Medical Center Portsmouth. Disclaimer. Nothing to . disclose. The . views expressed in this . presentation . are those of the author(s) and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States . What causes Lupus? Genes No gene or group of genes has been proven to cause lupus. Lupus does, however, appear in certain families, and when one of two identical twins has lupus, there is an increased disease that ravages dierent parts of the body. Research shows lupus is more pervasive and more severe than people think, and has an impact that the public doesn’t realize. You can change t Presented by: Olivia Wassef What is Systemic Lupus Erythematosus (SLE)? • An Autoimmune Chronic Inflammatory Disease ▫ Immune System produces proteins called autoantibodies that turns against 09/11/2013. SLE. An autoimmune disease . of the body's connective tissues, primarily the immune system attacks parts of the cell nucleus. It is a Type III hypersensitivity reaction caused by antibody-immune complex formation. . Autoimmune disease is a group of disorders in which tissue injury is caused by humeral (by auto-antibodies) or cells mediated immune response (by auto reactive T cells) to self antigens.. Normal, the immune system does not attach the self. However, there is a large . . By. Dr. Muhammad Abdullah Shwani. Assistant professor/Consultant urologist. Kurdistan Higher Council of Medical Specialties (KHCMS). drmalshwani@mail.com.