PPT-Validation of an LC-MS/MS Method for Quantification of Fumonisins in Garlic

Francesca Rossi 1 Khuong Hua 2 Jeremiah Dung 2 Jennifer Duringer 1 1Department of Environmental amp Molecular Toxicology Oregon State University Corvallis OR   2  Department Botany amp Plant Pathology Oregon State University Central Oregon Agricultural Research and Extension Center Madras OR . Bob Seevers. Importance . of . Analytical Methods . in . Development Stability Studies. Without analytical methods it is not possible to know what has happened during stability. Assay. Impurities/Degradation Products. . Bujji Kanchi. Main Objective works for stability. Before performing stability studies, a stability indicating method is necessary so that any possible degradants generated during storage conditions (such as 5°C, 25°C/60%RH and 40°C/75%RH) can be separated, detected, and . OVER VIEW :-. OPERATING METHOD :- . ASSEMBLY PROCEDURE :-. MARKETING. :-. ADVANTAGE :-. Estimate project cost and time:-. OVER VIEW :-. Operating speed : . 550 . rpm. Specification :-. Handle. Cover. Patricia Hanson, Biological Administrator I. Florida Department of Agriculture and Consumer Services, Food Safety Microbiology Laboratory. Introduction. 17 years in the microbiology section of the Florida Department of Agriculture and Consumer Services, Food Laboratory. OVER VIEW :-. OPERATING METHOD :- . ASSEMBLY PROCEDURE :-. MARKETING. :-. ADVANTAGE :-. Estimate project cost and time:-. OVER VIEW :-. Operating speed : . 550 . rpm. Specification :-. Handle. Cover. Patricia Hanson, Biological Administrator I. Florida Department of Agriculture and Consumer Services, Food Safety Microbiology Laboratory. Introduction. 17 years in the microbiology section of the Florida Department of Agriculture and Consumer Services, Food Laboratory. BY . Dr. . Alka. N . Choudhary. Division of Pharmaceutical Sciences. S.G.R.R.I.T.S., Patel Nagar, Dehradun (UK). “. Validation of an analytical procedure is the process by which it is established, by laboratory studies, that the performance characteristics of the procedure meet the requirements for its intended use.”. BY . Dr. . Alka. N . Choudhary. Division of Pharmaceutical Sciences. S.G.R.R.I.T.S., Patel Nagar, Dehradun (UK). “. Validation of an analytical procedure is the process by which it is established, by laboratory studies, that the performance characteristics of the procedure meet the requirements for its intended use.”. Analytical Method development . Computer system validation, ERP. 1. LIST OF CONTENTS. Process validation. Introduction . Type of validation . Stage of validation. Major phase of validation. SOP. Validation report. Assay Optimization pre- Assay optimization and pre-validation are experiments that determine how a range of matrix and sample elements as well as assay conditions effect assay parameters and assay p Bioanalytical Method ValidationGuidance for IndustryUS Department of Health and Human ServicesFood and Drug AdministrationCenter for Drug Evaluation and Research CDERCenter for Veterinary Medicine CVM Cryostat Finite . Element Model with Unique . FE Method. (FIP/P8-22 . ). The ITER Cryostat—the largest stainless steel vacuum pressure chamber ever built which provides the vacuum environment for components operating in the range from 4.5 k to 80 k like ITER vacuum vessel and the superconducting magnets. . Introduction, definition & general principles of calibration, qualification & validation, importance & scope of validation, types of validation, validation master plan, calibration of pH meter, qualification of UV-visible spectrophotometer, General principles of analytical method validation. Roy van . Brummelen. BPharm. , MSc, PhD, . DTech. Institute for Pharmaceutical Services. &. Van . Brummelen. Consultants. royvbc@gmail.com. Method Development & Validation. Specificity. Linearity and range (standard & sample).