PPT-Pharmacogosy Lec . 1 Alkaloids

Alkaloids Definition Alkaloids are natural compounds display an expceptionally wide array of biological activities and have a wide distribution being present in plants fungi bacteria insects marine animal and man. Precursor is formed by combining two C. 6. C. 2. units, both originating from tyrosine. Focus: . pieces/precursors. key assembly steps. structure-activity. physiological interactions. First . methylation. Sugar + non-sugar. In the body they are broken down by enzymes or acids into:. sugars= . glycone. / water soluble. non sugar= aglycone/ active portion. Aglycone may be an alcohol, sulfur or phenol compound.. . Alkaloids. Prof. Dr. İhsan . ÇALIŞ. References. . R. . Hänsel. &O. . Sticher. , . Pharmakognosie. , . Phytopharmazie. , . Springer. , . Heidelberg. 2007 . J. . Bruneton. , . Pharmacognosy. Prepared By. Dr. Khalid Ahmad Shadid. Chemistry Department – Islamic University in Madinah . Islamic University in . Madinah. Department of Chemistry. CH-3. ALKALOIDS. What is Alkaloids: . Alkaloids means . alkaloids. Vinca. , . Rauwolfia. , Ergot, . Nux. . vomica. Indole. Alkaloids. Ergot . Alkaloids. Occurrence:. . Ergot. is the dried . sclerotium. . of a . fungus. ,. . Claviceps. . purpurea. Alkaloids. TROPANE ALKALOIDS. The . tropane. alkaloids, which have the . 8-azabicyclo . octane . nucleus. , are commonly found in plants of three . families;-. Solanaceae. Erythroxylaceae. Convolvulaceae. Tahir Ali. Lecturer. RIPS, RIU. Any. Guess. Please . VOMIT. answer of some kind. Definition. Alkaloids. are extremely difficult to define because of two major reasons: . T. heir diverse heterogeneous nature . HPTLC–FLD/MS. Claudia Oellig. Institute . of. Food Chemistry, University . of. . Hohenheim. Germany. HPTLC-FLD. ERGOTS. Ergots. . Produced by parasitic fungi, e.g. . Claviceps. . purpurea. . 5. Quinoline. alkaloids. Alkaloids containing . quinoline. as their basic nucleus include those obtained from cinchona bark (. Cinchona . succirubra. ) ( quinine, . quinidine. , . cinchonine. , and . İhsan . ÇALIŞ. References. . R. . Hänsel. &O. . Sticher. , . Pharmakognosie. , . Phytopharmazie. , . Springer. , . Heidelberg. 2007 . J. . Bruneton. , . Pharmacognosy. : . Phytochemistry. - . 3rd Class, 2nd Semester. They are ester alkaloids resulted from the coupling of organic acids with amino alcohol (Base).. Introduction. Tropane Alkaloids are classified into. :. . 1- . Solanaceous Tropane Alkaloids. INDOLE ALKALODS. a class of . alkaloid.  containing . a structural moiety of . indole. ; many . indole. alkaloids also include.  . isoprene.  groups and are thus called . terpene. . indole. . or . Aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa. Mariana C. Almeida. 1,2. , . . 1- Definition : Secondary plant products act as acid and base at the same time. : . 2-Occurance. ( . Solanaceae. – . Papaveraceae. - . Liliaceae. ) . . 3- Distribution. CHNO and the end ne ).