PPT-Molecular Biology of Genes

A review Ross Hardison Dec 18 2014 1 What are genes Dec 18 2014 2 Characteristics of Genes Units of heredity Determine heritable phenotypes Are mutable allelic variants Are on chromosomes. Over the past decade an ever growing arsenal of techniques has helped researchers dissect the innermost secrets of the cell and develop new ways to detect and attack disease These techniques also have been used to produce vast amounts of once rare d Basic molecular biology techniques. Isolating nucleic acids. Cutting DNA into fragments. Ligating DNA fragments. Amplifying DNA fragments. Hybridization techniques. Genomics. Sequencing genomes. Analyzing genome sequences. Spring . 2012. “Problems” with morphological. data…. Convergence and parallelisms. Reduction and character loss. Phenotypic vs. genotypic differences. Evaluation of homology. Misinterpretation of change or polarity. Cancer Informatics (omics). David Boone. Outline. What is cancer and how is it different from other diseases?. Major players in tumor initiation (Understand one before many) . Oncogenes. Tumor suppressors. Basic molecular biology techniques. Isolating nucleic acids. Cutting DNA into fragments. Ligating DNA fragments. Amplifying DNA fragments. Hybridization techniques. Genomics. Sequencing genomes. Analyzing genome sequences. Cancer Informatics (omics). David Boone. Outline. What is cancer and how is it different from other diseases?. Major players in tumor initiation (Understand one before many) . Oncogenes. Tumor suppressors. Spring . 2012. “Problems” with morphological. data…. Convergence and parallelisms. Reduction and character loss. Phenotypic vs. genotypic differences. Evaluation of homology. Misinterpretation of change or polarity. Split . genes: Exons and introns. Chromatin structure and . states: Epigenetics. 12/21/14. 1. Classification by +/- nucleus. Prokaryotes: Organisms whose cells lack a nucleus. Bacteria and . Archaea. . . Asst. . Prof. Dr. . Dalya. Basil Hanna. . . Molecular Biology of Cancer. Normal cells have a defined lifespan – they grow, divide, and die in an orderly fashion. A . Upgraded Lecture Note Series Jimma Universit y MOLECULAR BIOLOGY AND APPLIED GENETICS Lecture Note Series Democratic Republic of Ethiopia Ministry of Education and Ministry of Health The problem fa Institute of Medical S ciences (IMS) Banaras Hindu University (BHU) Varanasi - 221005 Junior Research Fellow Applications are invited for the one post of the Junior Research Fellow ( JRF ) with a s ;. . the. . study of . biology. at the . molecular. level.. Molecular biology. ;. . the. . study of . gene . structure and functions at the . molecular level. . to understand the molecular basis of hereditary, genetic variation, and the expression patterns of genes. . Biology and its complexity. Our own efforts here at . Colaba. campus: . A. brief introspection. CONCLUDING THOUGHTS . Where is Biology headed?. Biologists. Want to understand organisms and living systems. Biochemistry examines the rudimentary chemistry of life. Molecular biology studies the complex interactions among biological molecules. ASBMB publishes three prestigious research journals. ASBMB's journals publish original research in the fields of microbiology, molecular genetics, RNA-related research, proteomics, genomics, transcription, peptides, cell signaling, .