PPT-iJOURNAL CLUB: Optimizing Therapy for Patients with Metastatic Squamous Cell Carcinoma

Interview with Shirish M Gadgeel MD January 14 2020 Case 1 72yearold woman enrolled on KEYNOTE021 2014 72yearold female patient with chest pain cough and dyspnea is diagnosed with Stage IV squamous cell carcinoma. BIO . 218 Human Anatomy. Summary: . What is Lung Cancer?. Lung Cancer is the growth of abnormal tissue characterized by the progressive, uncontrolled multiplication of cells. This abnormal growth of new cells does not develop into healthy lung tissue but rather manifest into a . PD-L1 is a transmembrane protein involved in regulation of cellular and humoral immune responses. PD-L1 is mainly expressed on antigen presenting cells, activated T and B cells, placenta. PD-1 (receptor) is broadly expressed on activated lymphoid cells. It is also highly expressed on regulatory T cells, and over-expressed on exhausted T cells. Interaction of PD-L1 with receptor PD-1 helps regulate T cell activation and tolerance during pregnancy, tissue allografts, and in autoimmune disease.. WHAT THE PRACTICING PATHOLOGIST OR ONCOLOGIST NEEDS TO KNOW. (SUPPLEMENTARY SLIDES). Steven J. Kussick, MD, PhD Associate Medical Director. PhenoPath Laboratories. May 2016. Other Hematolymphoid Disorders, . Nonlinear optical imaging as a diagnostic tool for cutaneous squamous cell carcinoma Giju Thomas (2015) INVITATIONTo the public defense ofthe PhD thesisimaging as a diagnostic tool for cell carci . with. . extended. vaginal . intraepithelial. . neoplasia. (VAIN) in a . patient. . with. . Müllerian. . Agenesis. (Mayer-. Rokitansky. -. Kuster. -Hauser Syndrome MRKHS) 41 . yrs. after . Branchial cleft cyst presenting as metastatic squamous carcinoma in fine needle aspirates 43 Imaging techniquesused for these patients can yield incorrect results. In fact, inour Case 1, MRI performed 366 Placental site nodule (PSN) is a non-neoplastic infrequent lesion originating from the intermediate trophoblast, which theoretically represents a non-in-voluted portion of placental tissue. This l diameter. There were no palpable groin lymph nodes.Ultrasonography and magnetic resonance imaging (MRI) revealed a complex cystic mass on the posteromedial aspect of the left thigh with irregular wal $% 

   
& %
' 
()) 

" 
3%)
4
)56# #%#5 PrjotJSS image showing high signal intensity at the right cerebellopontine angle A oomjoeہNMConn was p CESC. CESC. CHOL. CHOL. COAD. COAD. DLCB. DLCB. ESCA. ESCA. GBM. GBM. HNSC. HNSC. A. B. C. D. E. F. G. H. I. J. K. L. Q. R. M. N. O. P. S. T. KIRP. KIRP. LAML. LAML. LGG. LGG. LIHC. LIHC. LUAD. LUAD. . . Squamous . oesophageal. cancer . is relatively . rare in . Caucasians (4/100 000), whilst in Iran, parts of Africa and China it is much more common (200 per 100 000). Squamous cancer can arise in any part of the . . Rosemary D. Cress, . DrPH. Amy K. Klapheke, MPH, PhD. Public Health Institute. Cancer Registry of Greater California. Introduction. Lung cancer incidence in California has declined steadily thanks to reduction in smoking. Addressing Practical Clinical Questions Across the Metastatic Lung Cancer Continuum. Friday, October 11, 2019. 6:15 PM – 7:45 PM . Chicago, Illinois. Faculty. . Moderator. Joel W Neal, MD, PhD. Nasser H Hanna, MD. A closer view of the lobar pneumonia demonstrates the distinct difference between the upper lobe and the consolidated lower lobe. . 1-Lobar pneumonia. Lobar pneumonia:. Section of the lung shows diffuse consolidation:.