PPT-Sodium-glucose link transporter-2 inhibitors in reduced renal function: Cross-class comparison

TSJ Crabtree 1 A Bickerton 2 K Dhatariya 3 A Gallagher 4 J Elliott 5 R Raghavan 6 IW Gallen 7 REJ Ryder 8 on behalf of all ABCD SGLT2 audit contributors 1 Diabetes amp Endocrinology Royal Derby Hospital University Hospitals of Derby and Burton NHS Trust UK Derby UK 2 Diabetes amp Endocrinology Yeovil District Hospital NHS Trust Yeovil UK 3 Diabetes amp Endocrinology Norfolk and Norwich University Hospitals NHS Trust Norwich UK 4 Diabetes amp Endocrinology University Hospitals of Leicester NHS Trust Leicester UK 5 Diabetes amp Endocrinology Sheffield Teaching Hospitals NHS Trust Sheffield UK 6 Diabetes amp Endocrinology The Royal Wolverhampton NHS Trust Wolverhampton UK 7 Diabetes ampEndocrinology Royal Berkshire Hospitals NHS Trust Reading UK 8 Diabetes amp Endocrinology Sandwell amp West Birmingham Hospitals . Basic renal functions. Fluid balance. . Electrolyte balance. . Elimination of metabolic waste products. . . Components of the system. . Urinary bladder and associated plumbing. Summary. How do materials get across a cell's membrane. ?. It depends on the type of substance. Summary. Non-polar materials or hydrophobic materials . do. cross easily, especially if small. Ex – CO. Anatomy. The kidneys are a pair of fist-sized organs that are located on either side of the spinal column.. A kidney consists of an outer layer (renal cortex) and an inner region (renal medulla).. The functional unit of the kidney is the nephron.. Done by: Sahar Al-Subaie. Redox. titration:. . Redox. titration (also called oxidation-reduction titration) is one type of titration based on a . redox. reaction between the . analyte. and . titrant. Roland Halil, . BScPharm, ACPR, PharmD. Clinical Pharmacist, Bruyere Academic Family Health Team. Assistant Professor, Dept of Family Medicine, U of Ottawa. July 2016. Objectives. List the classes of oral antihyperglycemic agents and understand their place in therapy.. 24. th. November 2016. Andrew Gallagher. Consultant Physician. and Endocrinologist. NHS Greater Glasgow & Clyde. Prevalence – 2015 data. WORLDWIDE. . Almost 300 million people with diabetes aged 20-79. Inhibitors. anodic inhibitors. : . p. hosphates. s. ilicate . c. ompounds. . Cathodic inhibitors. poly-p. hosphates. . Ca(HCO3)2. methylamino-phosphate. (c). . mixed anodic and cathodic inhibitors. Ominous Octet. Renal Handling of Glucose. Active (SGLT2) and Passive (GLUT2) Glucose Transport in a Renal Proximal Tubule Cell. Renal Glucose Transport . GLUTs . Altered Renal Glucose Control . in T2D. renal pelvis. The modi?ed ?uid from the original ?ltrate . The ?ltrate contains diffusible constituents at . ?ows from the collecting ducts into the renal tract. . almost the same concentrations as in plasma. About . 1. By Anil K. Mandal, MB, BS,. Fulbright Scholar. Consultant in Nephrology. Courtesy Clinical Professor of Medicine, University of Florida, Gainesville, Florida. Mandal Diabetes Research Foundation. tax-exempt charitable organization. Dr Shivam Patel. Shivam.Patel@doctors.org.uk. 1. Contents. Sodium balance. Potassium. Pituitary and Adrenals. Thyroid . Metabolic disorders. Renal (AKI, CKD and measuring function). Enzymes and cardiac markers. ��Version 1.0NAME OF THE MEDICINAL PRODUCT Lisinopril dihydrate. The chemical name for lisinopril dihydrate is N N-[(1S)carboxyphenylpropyl] New Zealand Data SheetLisinopril (Ethics)Lisi By . Dr.Qutaiba. . Abdulkareem. . Qasim. 2020. Topics to be discussed. 1-Renal function :. Renal glomerular function . Renal tubular function . Water reabsorption: urinary concentration and dilution . . Diabetes action Canada annual workshop. Friday, MAY 31, 2019 . Bruce A. Perkins, Leif E. Lovblom, Nancy Cardinez, Andrej . Orszag,. Marcelo . Falappa, Devrim Eldelekli, Daniel Scarr, Ahmad Haidar.