PPT-What can we do about repeats?

Two main approaches Cluster the reads Link the reads What can we do about repeats Two main approaches Cluster the reads Link the reads What can we do about repeats Two main approaches Cluster the reads. de novo. repeat detection in genomic sequences. Do Huy Hoang. Outline. Introduction. What is a repeat?. Why studying repeats?. Related . work. SAGRI. Algorithm. Analysis. Evaluation. Introduction. What is a repeat? (Definition). Tandem repeats transposon CAGCAGCAGCAGCAGCAGCAGCAGCAGCAG... Much of the sequence between its genes consists of tandem 7-nt repeats, unique (so far) amongst bacteria. Some appear to f Geobacillus. and . Heamophilious. . Phages. Ramey . Elsarrag. Introduction. Tandem repeats are adjacently repeated patterns of DNA sequences. They are associated with genetic instability and are used for forensic identification. Nick Turner. Bio 446 Fall 16. Review. siRNA. dsRNA. microRNA. Immunity. Gene Regulation. Enzymatic breakdown of RNA. RNA Interference. RNAi. The use of RNA to inhibit gene expression.. Guiding RISC (RNA Induced Silencing Complex) cleave and degrade specific segments of RNA. Miguel . Andrade. Faculty of Biology, . Johannes Gutenberg University . Institute of Molecular Biology. Mainz, Germany. a. ndrade@uni-mainz.de. Repeats. Frequency. 14% proteins contains . repeats. . BY: William Gittens +. Sam . J. ackson. What is a Tandem Repeat?. It is a DNA pattern of two or more nucleotides. This pattern is repeated and the repetitions are directly adjacent to each other . Uses . Repeats. Frequency. 14% proteins contains . repeats. . (. Marcotte. et al, 1999). 1: Single . amino. . acid. . repeats. .. 2: . Longer. . imperfect. . tandem. . repeats. . . Assemble. in . structure. Miguel . Andrade. Faculty of Biology, . Johannes Gutenberg . University . Mainz, Germany. a. ndrade@uni-mainz.de. Repeats. Frequency. 14% proteins contains . repeats. . (. Marcotte. et al, 1999). 1: Single . Do Huy Hoang. Outline. Introduction. What is a repeat?. Why studying repeats?. Related . work. SAGRI. Algorithm. Analysis. Evaluation. Introduction. What is a repeat? (Definition). [General]: Nucleotide sequences occurring multiply within a genome. Fourth grade. First semester. 2018-2019. بسم الله الرحمن الرحيم. Diagnostic Medical Microbiology-Laboratory Manual. What Is a DNA Fingerprint?. Every individual carries a unique set of genes. Chromosome. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. Simple repeats (micro-satellites). Low complexity repeats. DNA repeat elements (DNA). Long terminal repeat elements (LTR). Unknown. Long interspersed nuclear elements (LINE). Genetics Pedagogies Project. Annie Jamieson (A.K.Jamieson@leeds.ac.uk). recap. Continuity and variability. Genes/ Environment/ Chance in development. Structure and function of DNA and chromosomes. How these ensure both continuity and variability. TWO TYPES OF FINGERPRINTS ARE KNOWN SO FAR !. Continued . Conventional fingerprint . of an individual comes from . finger tip . and unique for an . individual.. This . is used for identification of a person in forensic lab, police station etc. . Dispersed repeats:. Transposable Elements. Repetitive DNA sequences. Nuclear Genome. Tandem repeats. Class II. DNA . transposons copied and moved via DNA. Class I Retrotransposons . amplifying via an RNA intermediate.