Genome sequencing and assembly
MayoUIUC Summer C ourse in Computational Biology Session Outline Genome sequencing Schematic overview of genome assembly a DNA is collected from the biological sample and sequenced b The output from the sequencer consists of many billions of short unordered DNA fragments from random positions in the genome c The short fragments are compared with each other to discover how they overlap d The overlap relationships are captured in a large assembly graph shown as nodes representing
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