PPT-3.4 Inheritance How Genetic Information Is Passed On

Understanding Mendel discovered the principles of inheritance with experiments in which large numbers of pea plants were crossed Gametes are haploid so contain one allele of each gene Two alleles of each gene separate into different haploid daughter nuclei during meiosis. INTRODUCTION TO GENETICS. APPLIED GENETICS. Chapter 14A: INTRODUCTION TO GENETICS. Mendel. Rules and Terminology for Examination of Genetic Inheritance. Expanding the Rules and Terminology to follow two (or more) genes in a cross. 5.3- . Following. Patterns . of . Inheritance. in . Humans. What is a Pedigree?. Flowchart; “Genetic Family Tree. Symbols show inheritance patterns of traits over generations. Used to determine presence/absence of an allele responsible for disease in an individual.. Employment and Health Insurance. Why GINA?. What is Genetic Information?. . Information about:. A person’s genetic . tests. Genetic tests of a person’s family members. Disease or disorder in a family member. Inheritance . and The complex genetics of common . disorders. . Human Genetics. Genetics 202. Jon Bernstein. Department of Pediatrics. October 8, 2015. Session Goals – Non-Mendelian Inheritance. Understand how imprinting occurs and gain familiarity with conditions in which imprinting plays a role.. Overview of Genetics. Genetics – Overview. Genetics is the study of heredity and variation . Genetics is the unifying discipline in biology. Explains why organisms have certain traits . How traits are passed from parent to offspring. Genetic disorders can be due to any of the following factors:. A. Monogenetic Disorders: Caused by a mutation in a single gene. Autosomal. recessive alleles:. a. You may be a carrier and not know it, since the dominant allele masks the recessive.. Polydactyly. Down Syndrome. Hemophelia. Progeria. Hypertrichosis. Sickle Cell Anaemia. INTRODUCTION. What is genetic diseases/disorders?. The human body is composed up of cells , each one specializing a particular function like sensing light, smelling . October 19. th. – October 30. th. March 27. th. – March 31st. Female Karyotype . *Karyotype: the complete set of chromosome in the cells of an organism. *Homologous chromosomes: there are two copies of each chromosome; same size, same shape, same genes. University of . Basrah. Al-. zahraa. medical college. . . Human Heredity . Chapters 2, 3, 4, 5. . Lippincott’s . Illustrated Reviews: Cell and Molecular Biology Chapter . The production of gametes (sex cells). Males = spermatogenesis in the testes. Females = oogenesis in the ovaries. Mitosis vs Meiosis. (Remember). . Diploid. Contain the full number (set) of chromosomes. Inheriting Genetic Conditions Reprinted from https://ghr.nlm.nih.gov/ Lister Hill National Center for Biomedical Communications U.S. National Library of Medicine National Institutes of Health Departm Tel. No. 2419677/2419361 e - - mysore.ac.in Fax: 0821 - 2419363/2419301 www.uni - mysore.ac.in UNIVERSITY OF MYSORE Estd. 1916 Vishwavidyanilaya Karyasoudha Crawford Hall, Mysuru - 570 005 N Complex Patterns of Inheritance. Incomplete dominance (review). Co-Dominance (review). Multiple alleles – pattern of inheritance is determined by two or more alleles. . Blood types (next slide) – three forms (I. TERMINOLOGY OF GENETIC AND CONGENITAL DISORDERS. Congenital. Allele. Gene locus. Gene mutation. Genotype. Phenotype. Homozygous. Heterozygous. Polymorphism. Gene penetrance. Gene expression. CAUSES OF BIRTH DEFECTS.