Fasciola hepatica is associated with increased risk of verocytotoxin producing Escherichia coli O157 from an existing study protocol Poster P1 G 087 GL Hickey PJ Diggle TN McNeilly SC Tongue ME ChaseTopping DJL Williams ID: 1047752
Download Presentation The PPT/PDF document "The feasibility of testing whether" is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
1. The feasibility of testing whether Fasciola hepatica is associated with increased risk of verocytotoxin producing Escherichia coli O157 from an existing study protocol (Poster # P1 G 087)GL Hickey, PJ Diggle, TN McNeilly, SC Tongue, ME Chase-Topping, DJL WilliamsObjectiveAssess whether there is a statistically significant association between F. hepatica and E. coli O157 in cattle No funding for a dedicated study, so explore feasibility of augmenting a planned FSA studyMethodsSimulate multiple synthetic datasets that approximately match the FSA study design, with infection prevalences based on previous studies, and a clinically relevant odds ratio of 2Fit random-effects logistic regression models to the simulated datasets to calculate the powerConclusionsFrom a potential 270 farms, we can achieve 87% power to detect a co-infection association by testing 50 farms for both infectionsPower