PPT-Neoplasia and Tumor Biology

Neoplasia is a process of new growth in which normal cells undergo irreversible genetic changes which render them unresponsive to ordinary controls on growth exerted from within the transformed cell or by surrounding normal cells. . Cancer. Neoplasia. A Disorder of Altered Cell Differentiation and Growth. Cancer. The second leading cause of death in the United States. Estimated 1.45 million diagnosed. 559,650 die each year. Prostate is the most common cancer for men. OBJECTIVES/RATIONALE. A neoplasm is an abnormal growth of tissue that may be benign or malignant. The student will identify terms related to neoplasia, classifications of tumors, and grading and staging of cancer.. Today’s Frontier. CNS Neoplasia- -Dogs. Common Types. Meningioma. Astocytoma. Oligodendroglioma. Choroid plexus . papilloma. Lymphoma. Neuroectodermal. tumors. Metastatic tumor. CNS Neoplasia- -Dogs. Dr. . Salma. . Mansoor. Lecturer,. DCOP,. DUHS. Definitions. Neoplasia = new growth. Tumor= swelling due to inflammation. Oncology= oncos is tumor, logy is study. Cancer= malignant tumors (crab). NEOPLASM. A neoplasm is an abnormal growth of tissue that may be benign or malignant. The student will identify terms related to neoplasia, classifications of tumors, and grading and staging of cancer.. Cancer Statistics. normal cervical squamous epithelium.  at the left, but . dysplastic squamous epithelium.  at the right. Dysplasia is a disorderly growth of epithelium, but still confined to the epithelium. Dysplasia is still reversible.. PATHG4500 Fall 2019. Introduction. Recommended Textbook . The Biology of CANCER. Robert A. Weinberg. Second Edition. Cancer Biology PATHG4500-001. Meets on select Mondays and Wednesdays. Course Directors: Anna . Dr. . Heyam. . Awad. MD, . FRCPath. ILOS. 1.list the main environmental causative agents of cancer.. 2. understand the difference between direct and indirect acting chemical carcinogens.. 3. understand the pathogenesis of cancer development due to several etiologic agents.. Dr. . Heyam. . Awad. MD, . FRCPath. ILOS. 1. understand the concept of immune surveillance.. 2. list the most common tumor antigens and understand their origins.. 3. understand the mechanisms through which tumor cells evade the immune system.. khalifa. . Etiology of cancer . Many factors may play a role in etiology of cancer:.  . I. Geographical & environmental factors:. These factors . form about 65% of all cancer etiology, while genetic factor form about 26%- 42% of cancer etiology. DR.Eaman suud khalifa. Abnormal mass of tissue. , characterized by followings:- . Its . growth is uncoordinated & exceeded. with that of the normal tissues.. Neoplasm . LEC.1. Abnormal mass of tissue. , characterized by followings:- . Its . growth is uncoordinated & exceeded. with that of the normal tissues.. Neoplasm . persist its growth after the cessation of stimuli which cause the change.. r the Examination of Specimens From Patients W ith Carcinoma of the Pancreas Protocol applies to all epithelial tumors of the pancreas , including high - grade neuroendocrine carcinomas . Low - gr PROFESSOR, DEPT OF PATHOLOGY. SKHMC. The British oncologist . Sir Rupert Willis definition : . "A neoplasm is an abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissues and persists in the same excessive manner after cessation of the stimuli which evoked the change." .