PPT-Project: HIV RT inhibition

PREVIOUS PRESENTATION HIV BIOLOGY and PROJECT BASICS THIS PRESENTATION HIV THERAPY ITs DRAWBACKS and OBJECTIVES OF THE PROJECT TITAS MALLICK TITAS MALLICK UNIVERSITY OF CALCUTTA INTRODUCTION. 1 Competitive Inhibition Fig 8- 2 Competitive InhibitionCTEuli S + S E P + E c = K . ( [ c / K c / Vx sl re S bu i n a S bd t fee E a a s wre S bd c w S f fee E S Inhibition is a term used to describe the inability of a product being formed due to the presence of another substance (the inhibitor). Enzyme inhibition . can be competitive or noncompetitive. Competitive inhibition is caused when an inhibitor “competes” with the substrate in binding with the enzyme. Pratt & . Cornely. . Ch. 7. Other Factors. Other factors affect enzyme activity. Temperature. pH . pH Optimum. Determined by structural stability. Compartmentalization. Determined by active site residues. frequency first, the dog won't learn 1. No painful bites. 90% of puppies will stop if you give a high-pitched squeal or yelp. If ng the game. The other 10% and puppies who are tired or over-stimulated CROSSMODAL INHIBITION AND ENHANCEMENT &#x/MCI; 0 ;&#x/MCI; 0 ;AbstractAny instant of conscious perception is shaped by the differential contributions of all of our sensory organs. Complem By: . Jingtian. . Weng. , Cindy Nguyen, Cassandra Lee, Sarah Bento-De Sousa. Presentation Date: Sept. 13, 2016. PHM142 Fall . 2016. Instructor: Dr. Jeffrey Henderson. What is COX?. Two homodimer enzymes COX-1 and COX-2. Pratt & . Cornely. . Ch. 7. Enzyme Kinetics. How fast an enzyme catalyzed reaction goes. Why study enzyme kinetics?. Helps us understand mechanism of enzyme (how it works). Investigation of mutations in metabolic pathways. Pratt & . Cornely. . Ch. 7. Enzyme Kinetics. How fast an enzyme catalyzed reaction goes. Why study enzyme kinetics?. Helps us understand mechanism of enzyme (how it works). Investigation of mutations in metabolic pathways. The structure of a noncompetitive inhibitor does not resemble the substrate and does not compete for the active site. .. Learning Goal . . Describe competitive and . noncompetitive inhibition . and reversible and irreversible inhibition. Inhibition-. The decrease in enzyme activity/loss of activity. exert effect by decreasing . affinity of the enzyme for the substrate. decreasing the amount of active enzyme available for catalysis. by a combination of these effects. . Reji. Babygirija. 1,2,3. , . Michaela. Murphy. 1,2. , Shelly Shonsella. 1,2. , Sabrina Dumas. 1,2. , Victoria Flores. 1,2. , Cara Green. 1,2. , Heidi Pak. 1,2. and Dudley W. Lamming. 1,2,3. 1. Department of Medicine, University of Wisconsin-Madison, . McCann CM, Vyse AJ, Salmon R, Thomas D, Williams DJ, McGarry JW, et al. Lack of Serologic Evidence of Neospora caninum in Humans, England. Emerg Infect Dis. 2008;14(6):978-980. https://doi.org/10.3201/eid1406.071128. AMVAC Chemical Corporation. FMC Corporation. Gowan. Company. September 15-18, 2020. Outline of Presentation. Introduction to Testing Program (Rick Reiss) – 15 minutes. Experimental Procedures and Results (Jan Chambers) – 20 minutes. 1. , Shelby Sloan. 1. , Kris . Vaddi. PhD. 2. , Rosa . Lapalombella. PhD. 1. , . Jihye. Paik PhD. 3. , and Robert A. . Baiocchi. MD PhD. 1. et al. 1 . Division of Hematology, Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH, USA .