fever be treated in ICU patients with infection or sepsis Morten H Bestle MD PhD EDIC Ass Professor Nordsjællands Hospital Hillerød University of Copenhagen Denmark ID: 1036623
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1. Cooling in SepsisShould fever be treated in ICU patients with infection or sepsis?Morten H. Bestle, MD, PhD, EDIC, Ass. ProfessorNordsjællands Hospital, Hillerød, University of Copenhagen, Denmarkmorten.bestle@regionh.dkDepartment of Anaesthesia and Intensive Care34th SSAI Conference, Malmö 2017
2. Overall Conclusions 1Fever in infected patients in the ICU is associated with a lower mortality and shorter hospital stays.In infected ICU patients, antipyretic therapy seems to be safe, but does not reduce mortality or length of stay.In septic shock, antipyretic therapy by (external cooling to normothermia) show improved hemodynamics and reduced early mortality .
3. Overall Conclusions 2Mild induced hypothermia (MIH):Has multiple effects in septic shock.Animal studies of MIH for 24-72 hours generally show improved organ function and survival.Functional coagulation seem to be improved.It remains unclear whether MIH can improve the prognosis in septic shock.The CASS study will bring clarity to this.