PPT-Structures of influenza A drug and inhibitor molecules bound to proton-channel targets

Publication about this research JL Thomaston NF Polizzi A Konstantinidi J Wang A Kolocouris and WF DeGrado J Am Chem Soc 140 15219 2018 Work was performed at Lawrence Berkeley National Laboratory ALS Beamline 831 Operation of the ALS is supported by the US Department of Energy Office of Science Basic Energy Sciences program. forwarding brPage 8br brPage 9br brPage 10br brPage 11br brPage 12br The 100X Protease Inhibitor Cocktail is a clear colorless liquid Background In order to study speci64257c target proteins of interest proteasemediated degradation during the genera tion of protein lysates is to be avoided A loss of normal cellular c EoS. for. Compressed Baryonic Matter. ATHIC 14/11/12. Mannque Rho. (. Saclay. and . Hanyang. ). QCD Phase. . . . ???. . . Next Era. K. oRIA .  FAIR  LIGO. EoS. for T~ 60 . (Inorganic phosphate & Sodium fluoride) on the rate of an enzyme catalyzed reaction. Type of Inhibitors . There exist a number of molecular species which, in the presence of an . enzyme and its substrate. http://www.pi.hitachi.co.jp/rd-eng/product/industrial-sys/accelerator-sys/proton-therapy-sys/proton-beam-therapy/index.html. http://. www.uos.harvard.edu/ehs/radiation/how_dosimeter.shtml. http://www.upmccancercenters.com/cancer/prostate/radbratherapy.html. Lessons Learned from H1N1….Are We Ready For Another Pandemic?. OBJECTIVES. At the end of this session, the learner will be able to:. Understand and explain the public health implications of pandemic influenza. - Exploiting . the Benefits of Pencil Beam . Scanning. Niek . Schreuder. Vice President and Chief Medical . Physicist. Provision Health Care. OUTLINE. Classical Proton Radiation Therapy. Proton Pencil Beam Scanning. Two funded influenza vaccines. Key campaign messages. 2018 promotional campaign . Eligibility. Influenza - the disease. 2018 vaccines and strains. Precautions and contraindications. Influenza and healthcare workers. 1. DRUG NAMES. Chemical name. Development name used internally. Biologic drugs too complex to use chemical name. Non-proprietary name (generic name). Combination name for some combination drugs. Proprietary name (brand name). enzyme inhibitors (ACE inhibitors). inhibit the conversion of angiotensin I to angiotensin II.. The. . main . indications of ACE inhibitors are shown below.. Heart Failure. ACE inhibitors are used in all grades of heart failure, . Deborah E. Westbrook, B.S.,M.S., . RPh. Pediatric Clinical Pharmacist. Vidant. Medical Center. Greenville, North Carolina. Disclosure. I have no financial conflicts of interest. Off label uses of these medications will be discussed. The influenza virus group consists of three enveloped RNA members of the family Orthomyxoviridae:. influenza A, B, and C. . Influenza A . viruses are further classified into hemagglutinin (H) and neuraminidase. RNA virus. of the family . Orthomyxoviridae. that is responsible for the infectious disease . influenza. (or most commonly referred to as flu) in birds, various mammals (such as pigs) and humans. Typically, influenza is characterized by fever, sore throat, chills and other non-specific symptoms, it is a much more severe disease. It is spread around the world in seasonal epidemics and according to World Health Organization, these annual epidemics result in about three to five million cases of severe illness, and about 250 000 to 500 000 deaths.. Libby . Krcik. , BS, RT(T), Patrick Lee, MS, RT(T), CMD, . Mingcheng. . Gao. , PhD, Mark . Pankuch. , PhD,. Megan . Boroczk. , BS, William . Hartsell. , MD. Northwestern Medicine Chicago Proton Center.