PPT-The 1000 Genomes Project

Gil McVean Department of Statistics Oxford What is the 1000 Genomes Project A catalogue of all types of genetic variation including rare variants c 1 frequency obtained by sequencing . 0 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 1000 120 459 405 144 136 130 129 128 122 122 89 311 54 217 95 203 153 180 167 153 144 516 485 1001 SIGMA 1000 1000 1000 1000 1000 1000 100 & . Genome evolution. Genomes and Genome Evolution - BIOL 4301/6301. What to expect and some suggestions.. I . like think . of . myself as . fair but reasonably tough. I want people to do well but I’m not willing to compromise on the material or ethical guidelines to make it happen.. Ann . Lesnefsky. (Stanford University). Sarah Douglas (Harvard University). Julian . Damashek. (Stanford University). Bradley . Tolar. (University of Georgia). Hopkins Microbiology Course 2011. Comparative . Andrey Grigoriev. Director, Center for Computational and Integrative Biology. . Rutgers University. 2. What are we going to do?. Observe effects of fundamental processes. Estimate their relative contribution. from Biological . Problem to . Combinatorial Algorithms. (and back). Pavel Pevzner. Department of Computer . Science,. . University . of California at San Diego. What is the evolutionary scenario for transforming one genome into the other?. Production Genomics Facility. “. User facility. providing high-throughput DNA sequencing & analysis in support of DOE missions in alternative . energy. , . carbon cycling . & . bioremediation. 2014 Workshop. G . × . E ANALYSIS. Diego . Jarquin. Chicago, IL. December 10. Variance components for common . inbreds. and hybrids. Genomes to Fields . Inbred – Pollen DAP. Inbred – Plant height. DNA. Double helix. Bases. Sequence. Gene . Key words. Genome . Genome sequencing. Species . Human Genome Project. DNA. is found in the nucleus of a cell. It is a long molecule that carries a set of codes to make you unique.. Dr. Vladimir Teif. BS222 – Genome Science Lecture 1. Welcome to BS222 Genome Science!. Meet your lecturers. Vladimir Teif. (module supervisor). Leonard . Schalkwyk. Patrick . Varga-Weisz. Jordi . Paps. Hardison. . Genomics 2_2. 1/7/15. 1. Y Chromosome. 3 billion bp = 3 Gb. Chr1 247 Mb. Chr12 132 Mb. Chr22 50 Mb. A human . genome (. male). The . genome. is . all the DNA. in a cell.. All the DNA on all the chromosomes. Genomic Medicine. Update Session. Provided by Catherine Carpenter-Clawson Programme Manager, WE . GMC with Tracie Miles Genomics Champion RUH, Bath.. Courtesy . of . Genomics England. The Human Genome Project. Update and rationale. Low-pass sequencing (Goncalo). Analysis . Disease projects (Sardinia, T2D). A public database of. . SNPs. . and detectable . CNVs. with allele frequency. >1. % in each of multiple human population samples. Campadelli-Fiume G, Mirandola P, Menotti L. Human Herpesvirus 6: An Emerging Pathogen. Emerg Infect Dis. 1999;5(3):353-366. https://doi.org/10.3201/eid0503.990306. Chris Wragg, Lead Cancer Scientist, SWGLH. 6. th March 2019. Contents. 100,000 Genomes Project. National update. Update on the future genomic medicine service. National delivery of 100,000 . Genomes .