PPT-Respiratory Drug Development

Medicinal Chemistry III B Pharm Dr Bilal Al jaidi and Dr Pran Kishore Deb Assistant Professor Pharmaceutical Medicinal Chemistry Faculty of Pharmacy Philadelphia UniversityJordan. to Long Term . Training. Respiratory system. : increased vital capacity; increase in minute ventilation; increased strength of respiratory muscles; increase in oxygen diffusion rate. Just as there are cardiovascular adaptations to . Respiratory System: . Intakes oxygen. Releases carbon dioxide waste. Circulatory system:. Transports gases in blood between lungs and cells. Respiratory system works with Cardiovascular system. Respiratory system anatomy. Trachea, Bronchial Tree, Lungs. Trachea. Extends from larynx into the thoracic cavity where it splits into the left and right bronchial tree. Trachea. Structure. Lined with ciliated mucous membrane. Membrane filters out particles and moves them up to the pharynx where they can be swallowed. What it is and how it works. What is it?. The respiratory system is a system of organs in the human body that’s main task is to perform . respiration. . It is composed of 10 separate organs.. Respiration is the act or process of breathing.. Robert Padera, M.D., Ph.D.. HBTM. 235. September 21, 2015. rpadera@partners.org. Goals. To teach you everything something about respiratory physiology and pathology. To set the stage for lecture on lung transplantation. The . respiratory. system is the group of organs that . takes. in oxygen and gets . rid. of carbon dioxide. Respiration. is another name for . breathing. Respiration is the . transport. of oxygen from . HCT II. Asthma. Respiratory disease usually caused by a sensitivity to an allergen. Dust. Pollen. Animals. Food. Asthma Symptoms. Occurs when bronchospasms narrow openings of bronchioles, Mucus production increases, edema develops in the mucosal lining. Respiratory System. Air sac. air-filled spaces in the body. alveoli. very small air sacs; where air breathed in goes. Respiratory System. Bronchial tubes. two tubes at the end of the trachea, brings in air from trachea and helps clean lungs; one tube goes to right lung, one to left. Dr. Tara Husain. SIGN. EXTRATHORACIC AIRWAY OBSTRUCTION. INTRATHORACIC-EXTRAPULMONARY AIRWAY OBSTRUCTION. INTRAPULMONARY AIRWAY OBSTRUCTION. PARENCHYMAL PATHOLOGY. Tachypnea. +. +. ++. ++++. Retractions. Respiratory Therapists work to evaluate, treat, and care for patients with . lung. and . heart. disorders.. What kinds of patients do Respiratory Therapists Treat?. Lung disease patients. Heart patients. Nutrients. Oxygen. carbon dioxide. sodium . Which of the following is NOT a part of the process of respiration? . thoracic respiration. external respiration. internal respiration. ventilation. External respiration refers to the exchange of oxygen and carbon dioxide between: . Transports air into the lungs and facilitates the diffusion of oxygen into the blood stream. Receives carbon dioxide from the blood and exhales it. Organs of the Respiratory system. Slide 13.1. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings. Defined as the impairment of the lung’s ability to maintain adequate oxygen and carbon dioxide homeostasis.. Respiratory Failure - Definition. PaO. 2. < 60 mm Hg. and/or. PaCO. 2. > 50 mm Hg. Travis R. . Goodwin. 1. , . Dina . Demner-Fushman. 1. , Kin Wah Fung. 1. , . and . Phong. Do. 2. 1. . Lister Hill National Center for Biomedical Communications, . U.S. National Library of Medicine.