PPT-Inflammation A normal response of living tissues to injury. It prepares the tissue for

A dynamic process that lasts from a few minutes to a few years Depending on the extent of the injury the type of injury the vascularity of the tissue Protective Role . Immune . Response. and Inflammation. Inflammation-definition. R. eaction of . vascularized. living tissue to local injury. Acute inflammation. Chronic inflammation. Repair. Resolution. Abscess. Injury. Response. A review. The 3 Lines of Defense. FIRST line: Barrier protection. non-specific (treats . each pathogen the . same). acts to prevent the pathogen from getting into the body. skin, mucous membranes, tears, sweat. Its purpose is to . localize. ,. . eliminate. the injurious . agent, . remove . damaged tissue . and . replace. it with healthy new tissue (. repair. ). . It consist principally of vascular changes associated with leukocyte infiltration and systemic reaction.. Two potential effects of force. Acceleration. Deformation. Factors that determine injury. Magnitude of force. Material properties of tissues involved. Force and Its Effects. Small load—. elastic response. Acute. – quick onset, short duration. Adhesion. – a sticking together or binding of tissue fibers. Antiseptic. – a substance which prevents the growth of bacteria. Avascular. – without blood or . J. Matthew Velkey. matt.velkey@duke.edu. 454A Davison, Duke South (green zone). Cellular Adaptation to Injury or Stress. Injury or Stress. Increased demand. Decreased stimulation or lack of nutrients. ASSISTANT PROFESSOR. WEST MEDICAL WARD. MAYO HOSPITAL/K.E.M.U. 1. DEFINITION OF INFLAMMATION. . Inflammation is a defensive process that a living body initiates against local tissue damage. It takes the form of a complex reaction of blood vessels, certain plasma components and blood cells, and cellular and structural components of connective tissue. . Dr. . Shakir. H. Mohammed . Al_Alwany. LEC 2,3,4. Hyperplasia & Physiologic . Hyperplasia. HYPERPLASIA . Increase . in the number of cells . results in increase in size of the . organ. DR. AYSER HAMEED. The major local manifestations of acute inflammation, compared to normal . . Vascular . dilation and increased blood flow (causing erythema and warmth). . . E. xtravasation . and deposition of plasma fluid and proteins (edema), and . By Ajay Kumar What is inflammation? A normal response of living tissues to injury. It prepares the tissue for healing and repair. Ultimate goal is to replace injured tissue. EFFECT OF INFLAMMATION: Th 1 IN THE HEALING PROCESS by Keith Wassung 2 The role of inflammation in the process of healing has been misunderstood for many years. Recent neurological and immunological research has shed light . cell injury, as well as the necrotic cells and tissues resulting from. . the original insult, and to initiate the process of repair.. INFLAMMATION. Inflammation can be acute or chronic. Acute. . CARDINAL SIGNS OF INFLAMMATION. Rubor (redness). Tumor (swelling). Calor (heat). Dolor (pain). Functio laesa (loss of function). FACTORS INVOLVED IN PROTECTIVE RESPONSES AND BODILY REPAIR. Inflammatory reaction. TION. . & HEALING BY FIBROSIS. Al-Madena Copy CLS. 2. Definition of the tissue repair. :. . restoration of tissue architecture and. . function after an injury. It occurs by two types of reactions:.