PPT-Quasispecies Theory and the Behavior of RNA Viruses

Sumeeta Singh Steve Bowers Greg R ice Tom McCarty BINF 704 021913 What is a virus Viruses are obligate intracellular parasites Small infectious agents bearing nucleic acid instructions. Mike . Morain. Basic Lecture Structure. History of malware. Nature and operation of malware. Discuss means of identification, removal, and . prevention. Virtualization in malware. A Brief History. John Von Neumann. Chapters 12 and 13. Viral Characteristics and Structure. Why Viruses aren’t Alive. General Characteristics of Viruses. Name derives from the Latin for “poison”. Obligatory intracellular parasites. What is a Virus?. Very small . Non-living particle. Made up of nucleic acid. . and proteins. Can only reproduce by infecting living cells. Do not carry out respiration, grow or develop. Structure. Viruses have an inner core which contains either RNA or DNA. Viruses Are Not Cells!. There are several structural and functional differences between cells and viruses. The structural differences include:. No nucleus. No cell membrane. No organelles. The functional differences include:. CLS 212: Medical Microbiology. History. Through the 1800s, many scientists discovered that something smaller than bacteria could cause disease and they called it . virion. (. Latin word- poison. ).. Chapter 18. Are Viruses Alive?. As a group discuss for 1 minute. Be able to defend your answer for the class!. Are . VIRUSES. alive?. Growth and Development. Reproduce. Change Over Time. Obtain and Use Energy. Viruses . A nonliving (?) particle made of proteins, nucleic acids, and sometimes lipids (fats). Viruses only reproduce by infecting living cells. Most viruses can only be seen with an electron microscope. Renan Gross,. Omer Markovitch and Doron Lancet. Department of Molecular Genetics, Weizmann Institute of Science, Israel. ILASOL, 01/12/2013. 2. Outline. Main result: populations of the compositional assemblies of the GARD model behave in a way that is similar to that predicted by quasispecies theory. . EQ: Why are viruses considered to be non-
living?. Characteristics:. *Nonliving particles made of . nucleic acid. and a . protein coat . enlosed in a . capsid. shell... *In order to reproduce, all viruses must have a . Elliot J. Lefkowitz. Email. ElliotL@uab.edu. Web Site. http://www.genome.uab.edu. Office. BBRB 277A. Phone. 934-1946. Contact Information: Elliot Lefkowitz, Ph.D.. Associate Professor, Microbiology. Objectives. Quickwrite! . . . Based on what you remember about viruses and cells from IPC:. Differences between the two? . Similarities? . Examples of each?. Be prepared to share.. QuickShare!. Discuss what you wrote with your table partner. . viral . quasispecies. reconstruction from next-generation sequencing data and vaccine optimization. PD: Ion M. ă. ndoiu. , . UConn. Co-PDs: . Mazhar. Khan, . UConn. Rachel O’Neill, . UConn. Alex . As a group discuss for 1 minute. Be able to defend your answer for the class!. Are . VIRUSES. alive?. Growth and Development. Reproduce. Change Over Time. Obtain and Use Energy. Maintain Homeostasis. DR MONIKA RAJANI . ASSOCIATE PROFESSOR ,. DEPT OF MICROBIOLOGY. CIMSH ,LKO. Dr Monika Rajani. Dr Monika Rajani. VIRUSES. Neither prokaryotes nor eukaryotes. No cellular . organisation. .. Contain . either DNA or RNA .