PPT-single strand, negative sense RNA Viruses

Elliot J Lefkowitz Email ElliotLuabedu Web Site httpwwwgenomeuabedu Office BBRB 277A Phone 9341946 Contact Information Elliot Lefkowitz PhD Associate Professor Microbiology Objectives. Chapters 12 and 13. Viral Characteristics and Structure. Why Viruses aren’t Alive. General Characteristics of Viruses. Name derives from the Latin for “poison”. Obligatory intracellular parasites. SC.L.16.3 . Describe . the basic process. of . DNA replication . and how it relates . to the . transmission . and . conservation. of . the genetic information. DNA and Its structure. DNA (deoxyribonucleic acid) is a large organic. Introduction to Basics . Dr.T.V.Rao MD. Dr.T.V.Rao MD. 1. History Virology. Smallpox was endemic in China by 1000BC. In response, the practice of . variolation. was developed. Recognizing that survivors of smallpox outbreaks were protected from subsequent infection, variolation involved inhalation of the dried crusts from smallpox lesions like snuff, or in later modifications, inoculation of the pus from a lesion into a scratch on the forearm of a child. . Take a notes sheet from the front table. Get out your warm-up sheet & answer the following:. What is the complementary strand for the below DNA strand?. ACTGCACCTGAGCGTATTGAC. TGACGTGGACTCGCATAACTG. bellringer. sheet:. Replicate the following DNA sequence. AGGTATCAG. Please add questions (at least 2 questions per page) and a summary to your DNA Replication Mutation Notes. 3 things you learned. 2 things you found interesting. Inherited and transmissible by ingestion, transplant, and surgical instruments. Spongiform encephalopathies: Sheep scrapie, Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia, mad cow disease. Contig. :.  Several uses, all nouns. The term comes from a shortening of the word ‘contiguous’. A ‘. contig. ’ may refer to a map showing placement of a set of clones that completely, contiguously cover some segment of DNA in which you are interested. Also called the ‘minimal tiling path’. More often, the term ‘. Size of genome. Segmented or not. Site of replication.  . FAMILIES of NEGATIVE STRAND VIRUSES.  . NON-SEGMENTED (-)STRAND VIRUSES. .  . RHABDOVIRIDAE. Rabies, VSV, & Plant viruses .  . FILOVIRIDAE. By. Dr. R. C. . Nath. ; Associate Professor. Department of Zoology. Govt. Degree College, DMR. .. Structure of a DNA molecule. `. It . has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material. Transcription, translation and transport. Transcription of virus genome. In the summary of the scheme depicted . below, most . of the nucleic acid strands are . labelled. (+) . or (. −). This . labelling. Transcription, translation and transport. Transcription of virus genome. In the summary of the scheme depicted . below, most . of the nucleic acid strands are . labelled. (+) . or (. −). This . labelling. Viruses are very small – smaller than the smallest cell.. They are usually surrounded by a capsid of proteins.. For replication, viruses rely on their host cells . ie. ., the cells they infect.. Most viruses exhibit a limited host range- they typically infect only specific types of cells of one host species.. Topics. Week l:. -Introduction and General characters of viruses. . (History ,definition, and importance of study). . Viral . structure. Virus . structure and morphology. composition . 1- Former member of the . Papovaviridae. family. Similar to . polyomaviruses. in some respects, but with a larger genome (8 . kbp. ) and particle size (55 nm). . 2-There are many genotypes of human papillomaviruses, also known as .