Nano Particles Preparation and Bio toxicity Why Silver Silver is known to be bio toxic Silver ions and neutral atoms disrupts cell membranes and causes cell ruptures Once inside the cell silver binds to mitochondrial membrane and disrupts energy yielding reaction ie energy ID: 448595
Download Presentation The PPT/PDF document "Silver" is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
Slide1
Silver Nano Particles
Preparation and
Bio toxicitySlide2
Why Silver?
Silver is known
to be
bio toxic
.
Silver ions and neutral atoms disrupts cell membranes and causes cell ruptures
Once inside the cell, silver binds to mitochondrial membrane and disrupts energy yielding reaction, i.e. energy
(ATP) production
in the cell.
Hence, silver ions and neutral atoms can kill bacteriaSlide3
Practical Application
Food and drink storage in ancient civilization
Surgical instrumentation
Ointments
Wound dressings
Cavity
filling (amalgam)Slide4
What are nano particle? Why
nano
?
Atomic silver (uncharged) particles that are less than 100 nm in diameter
Nano particles
can disrupt
cell membranes more
locally, more effective in bio toxicity.Slide5
Redox Reaction
2 Ag
+
(
aq
) +
2 e
- -----> 2 Ag(s)Citrate ion -----> acetone – 1,3- dicarboxylate + CO
2
(g) +
2 e
-
______________________________________ +
2
Ag
+
(
aq
) + Citrate ion ----->
2
Ag(s) + acetone-1,3-dicarboxylate + CO
2
Slide6
Electron Transfer and Release of CO2Slide7
Size Capping by CitrateSlide8
Color to look forSlide9
Acknowledgement
Drs.
Elizabeth
Hagar-Barnard and Rashmi
Nanjundaswamy
for spearheading
the project
National Science Foundation for providing the funding Maria Escudero, Brian Williams, Rodolfo Orellana and Charlene Cuellar for their assistant.