PPT-DNA Form & Function Understanding DNA replication – and the resulting transmission

Understanding DNA structure and replication is a prerequisite for understandingusing the principal tools of molecular biology R R 0 R0 R0 0 R0 R0 R 0 R RR R0 0 R0 00 DNA Structure amp Replication. Understanding DNA replication – and the resulting transmission of genetic information from cell to cell, and generation to generation – lays the groundwork for understanding the principles of heredity. SC.L.16.3 . Describe . the basic process. of . DNA replication . and how it relates . to the . transmission . and . conservation. of . the genetic information. DNA and Its structure. DNA (deoxyribonucleic acid) is a large organic. DNA Structure. The discovery of the structure. Francis Crick and James Watson. The deoxyribonucleic acid (DNA) molecule is the genetic blueprint for each cell and ultimately the blueprint that determines every characteristic of a living organism. The DNA molecule was discovered in 1951 by Francis Crick, James Watson, and Maurice Wilkins using X-ray diffraction. . Models of DNA replication: Meselson-Stahl Experiment. DNA synthesis and elongation. DNA polymerases. Origin and initiation of DNA replication. Prokaryote/eukaryote models (circular/linear chromosomes). Understanding DNA replication – and the resulting transmission of genetic information from cell to cell, and generation to generation – lays the groundwork for understanding the principles of heredity. Learning Objectives. What happens during DNA replication?. How is a new polynucleotide strand formed?. Why is DNA replication known as ‘semi-conservative’?. Putting What We’ve Learnt So Far In To Context.... Objectives:. 1. Summarize the roles of the different enzymes involved in replication of DNA.. 2. Explain how the leading and lagging strands are replicated differently . Semiconservative. Replication. DNA REPLICATION. DNA IS COPIED. 1. DURING . S-phase. of . INTERPHASE. PREPARATION FOR CELL DIVISION. SEPARATION. 2. THE . STrAND. OF DNA IS . UNZIPPED. BY . HELICASE. 3. THE POINT OF SEPARATION IS CALLED THE . Yadi. Zhou. 2013.12.05. RecA. protein. 38 . kiloDalton. Essential for the repair and maintenance of DNA. A . RecA. structural and functional homolog has been found in every . species. Homologous protein in . By. Dr. R. C. . Nath. ; Associate Professor. Department of Zoology. Govt. Degree College, DMR. .. Structure of a DNA molecule. `. It . has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material. Directions: Front of card write term. On back write definition and draw picture . Chromosomes. Thread-like structure made of coiled DNA. Gene. Segment of DNA that codes for a specific trait. Nucleotide. Something to think about... When a species . reproduces. , there is . genetic continuity . maintained from one generation to the next.. WHAT . is responsible for this continuity?. HOW . does this continuity happen?. . REPLICATION – GENERAL PRINCIPLES. START. Must be ready . Must know where to start . FINISH. Must all finish . Must ensure that each piece of DNA is replicated only once . Therefore must know where to finish . Mitochondrial DNA replication. MtDNA. replication is not directly linked to the plant cell cycle, and . mtDNA. copy numbers can vary widely depending on the tissue and stage of development.. MtDNA.