PPT-Cancer Genomics Cancer Genomic testing for patients with melanoma

A 38yearold Caucasian female with a history of extensive tanning bed use has a longstanding mole on the right shin A biopsy of the lesion and subsequent histology confirmed a diagnosis of a nonulcerated superficial spreading melanoma Breslow thickness 18mm pT2a. Melanoma is a cancer that develops in melanocytes, the pigment cells present in the skin. It can be more serious than the other forms of skin cancer because it may spread to other parts of the body (metastasize) and cause serious illness and death. About 50,000 new cases of melanoma are diagnosed in the United States every year.. VICTORIAN MELANOMA SERVICEVICTORIAN MELANOMA SERVICE VICTORIAN MELANOMA SERVICEVICTORIAN MELANOMA SERVICEremoved before life threateningremoved before life threatening VICTORIAN MELANOMA SERVICEVICTOR Bioinformatics and Genomics. Applications:. Personalized cancer medicines. Disease determination . Pathway Analysis. Biomarker Discovery . An Interesting Point. “One . article estimated that the output from genomics may soon dwarf data heavyweights such as . Presentation by Stacey . Neumann . to 6. th. Graders at STEM Launch. Statement: . Skin cancer is rare.. False: . 1 in 5 Americans will get skin cancer in their lifetime.. Statement: . You can die from skin cancer.. NHGRI strategic plan. What does the NIH think genomics should be for the next 10 years?. [Nature, Feb. 2011]. The Essence of Genomics. (according to NHGRI). Comprehensiveness. . Genomics . aims to generate complete data sets. Although relatively easy to define and measure for a genome sequence, attaining comprehensiveness can be more challenging for other targets (for example, functional genomic elements or the ‘proteome’). 1. What, in general, is a melanoma?. A tumor of melanin-forming cells (. melanocytes. from the basal layer of the epidermis.). Typically a malignant tumor associated with skin cancer, it’s the most dangerous type of skin cancer (could spread and become lethal.). Associate Professor Elin . Gray. Melanoma . Research Group. School of Medical and Health Sciences. Edith Cowan University, Perth, Western Australia. Blood Biomarkers of Cancer. AutoAbs. Wan et al., Nature Reviews Cancer 2017. Dina Paltoo, Ph.D., M.P.H.. NIH Office of Science Policy. Laura Lyman Rodriguez, Ph.D.. National Human Genome Research Institute. October 4, 2017. Housekeeping. Participants must register to join the webinar. Alan . Christoffels. South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, South Africa, Secretariat: Public Health Alliance for Genomic Epidemiology. July 201 MaeÕr ddogfen yma hefyd ar gael yn Gymraeg. This document is also available in Welsh. #$%&'!#%()$*+,-./!01232! 1 Genomics for Precision Medicine Strategy Executive Summary New genetic and g Genomics and Society Nature (2014) “ …disorders not readily explained by standard tests can sometimes be diagnosed through genome sequencing and analysis.” The Origin of “Genomics& Lara K. . Goudsouzian. , Ph.D.. Associate Professor of Biology. DeSales. University. Lara.goudsouzian@desales.edu. Melanoma. Melanocytes. Produce Melanin. Melanin is a dark pigment. The melanin travels in vesicles called . Laura Yarram-Smith . Solid Tumour Lead SWGLH. July 2023. https://www.nbt.nhs.uk/south-west-genomic-laboratory-hub. Part of a Genomic Medicine Service. Bristol Clinical Genetics . Peninsula Clinical Genetics. Ravi Madduri. madduri@anl.gov. Joint work with Paul . Davé. , Lukasz . Lacinski. , Alex Rodriguez, . Dinanath. . Sulakhe. , Ryan Chard and Ian Foster. Globus Genomics is developed, operated, and supported by researchers, developers, and .