PPT-Changing the trajectory of drug R&D

Robert Plenge MD PhD ASBMR September 15 2016 Our two fundamental challenges Cost to develop an asset has increased by 13 rd since 2010 Average peak sales per asset has halved since 2010. Whist eery eo rt is made to ensure accuracy there may be phonetic or other errors depending on ineitabe a riations in recording 0uaity Pease do contact us to point out any errors 1hich 1e 1i endeaour to co rrect To reproduce any part o this transcri Road. . Networks. Renchu . Song, . . Weiwei . Sun, . . Fudan. University. Baihua Zheng, Singapore Management University. . Yu . Zheng, . Microsoft Research, . Beijing. Background. Big Data. Huge volume of spatial trajectories cause heavy burden to data storage and data process. p = 4k – 1 asymmetry theorem . for quadratic residues . by Jim Adams . Sources. Part I: Mathematics – Number Theory item 2A in www.jimhadams.com.. Part II: Mathematics – Number Theory item 2B.. Mission. Status Report for SBAG. Will Grundy. Lowell Observatory. New Horizons: To . Pluto and Beyond. Pluto-Charon. July 2015. KBOs. 2016-2020. Jupiter System. Feb-March 2007. The Initial Reconnaissance of The Solar System. ( 4 ( 5 ( 3 ( 2 (1 Pelvis Gait Manager User CCD IK System Trajectory Pelvis Trajectory Y - axis Ground Time Pelvis Particle Leg Spring Gravity Foot Touching the Ground Leg Compression Leg Max Co ASEN5050. Astrodynamics. Jon Herman. Overview. Low-thrust basics. Trajectory design tools. Real world examples. Outlook. Low-thrust. Electric propulsion. Solar electric propulsion (SEP). Nuclear electric propulsion (NEP). A Family Case Presentation. Avegail S. Estrella, MD. 2. nd. Year Resident. UP-PGH DFCM. Objectives. To present a family of a patient with ulcerative colitis. To discuss the interaction between ulcerative colitis and the dynamics of the family. . USING HIERARHICAL REGION-BASED . . AND . . TRAJECTORY-BASED CLUSTERING . . JaeGil. Lee, . Jiawei. Han, . . Xiaolei. . Li, . Hector Gonzalez. Department of Computer Science. The “Hopping” Concept. Land on a celestial body using engines, conduct surface operations, then re-ignite engines and ‘hop’ to a new location on said body.. . Can hop multiple times until fuel runs out.. of Massive Trajectory Data based on MapReduce. Qiang. Ma, Bin Yang (. Fudan. University). Weining. . Qian. , . Aoying. Zhou (ECNU). Presented By: . Xin. Cao (Aalborg University). Outline. Introduction . Cynthia Sung, Dan Feldman, Daniela . Rus. October 8, 2012. Trajectory Clustering. 1. Background. Noise. Sampling frequency. Inaccurate control. SLAM . [. Ranganathan. and . Dellaert. , 2011; Cummins and Newman, 2009; . February 2018. The Future of Gender. Introduction. Where are we now? . 100 years of Suffrage. Business & Political Representation. Among FTSE 100 CEOs in the fiscal year for 2016 there were: . 8 . La gamme de thé MORPHEE vise toute générations recherchant le sommeil paisible tant désiré et non procuré par tout types de médicaments. Essentiellement composé de feuille de morphine, ce thé vous assurera d’un rétablissement digne d’un voyage sur . Svetlana . Nedelcheva. 1. Embodiment and experience. 2. Our knowledge of the world is indirect because it is constrained by how we experience it. . Our experience of the world is always mediated via our uniquely human perceptual system, physiology and neural architecture.