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…next steps: the  CABOTO-C project …next steps: the  CABOTO-C project

…next steps: the CABOTO-C project - PowerPoint Presentation

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…next steps: the CABOTO-C project - PPT Presentation

CLIC RF structure development meeting 10032010 A Degiovanni U Amaldi R Bonomi M Garlasché A Garonna R Wegner S Verdú Andrés Hadron therapy the basics 10032010 ID: 802510

degiovanni tera foundation alberto tera degiovanni alberto foundation power 2010 mev energy caboto band hadron therapy ghz cyclotron 400

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Slide1

…next steps:the CABOTO-C project

CLIC - RF structure development meeting10.03.2010A. Degiovanni U. Amaldi, R. Bonomi, M. Garlasché, A. Garonna, R. Wegner, S. Verdú Andrés

Slide2

Hadron therapy

: the basics10/03/2010Alberto Degiovanni – TERA Foundation2

charged hadron beam

that loses energy in matter

27 cm

tumour

target

4800 MeV – 0.1 nA

carbon ions

(

radioresistant

tumours

)

200 MeV - 1 nAprotons

Photons

Protons

X

rays

protons or

carbon ions

tail

cobalt 60

e

-

linac

httt://global.mitsubishielectric.com/bu/particlebeam/index_b.html

light

ion (carbon

)

proton

Courtesy of PSI

Courtesy

of

PSI

Slide3

Accelerators for

hadron therapyRELIABILITY  stability of structure and beamPRECISION  3D

conformal treatment

FLEXIBILITY

accelerated

particles

,

energy

, intensity

SIMPLE OPERATION, REPAIRING

MODULARITY  installation and

maintenance…COSTS  compactness, power consumption10/03/2010

3

What

are

the

most important

characteristics of a hadron therapy center ?

…it’s

a COMPLEX PROBLEM, with

many possible solutions

!

Alberto

Degiovanni – TERA Foundation

Slide4

The CYCLINAC

solution10/03/20104

LIGHT = Linac

for Image

Guided

Hadron

Therapy

1993:

first

Cyclinac

proposal

2003:

test

on

LIBO-62

MeV (TERA-CERN-INFN)

2009:

LIGHT

production

(

ADAM=Application of Detectors and Accelerators

to Medicine)

2001: first IDRA-design

2007:

first

CABOTO

design

Alberto

Degiovanni – TERA Foundation

Slide5

S, C, X band SW / TW solutions (

A. Grudiev, X-band travelling wave structure for TERA, 2009-03-25)

C

band

,

5.7

GHz

X-band

11.4

GHz

L-band

1.3

GHz

Microwave Frequency SpectrumS-band 2.8

GHz

2007: CABOTO-S 300-430 for SCENT

2009: CABOTO-S 230-400 for Synchrocyclotron

10/03/2010

5

Review

of CABOTO

project

2010: CABOTO-C 120-400 for

K480 SC

Cyclotron

Alberto

Degiovanni – TERA Foundation

Slide6

LINAC

LengthIncrease in Effective Shunt ImpedanceFilling time reductionBreakdown limits - higher gradient

RF power source

availability

Transverse

emittance

constraints

Costs

of

high

precision machining

10/03/2010

6

vs.Higher frequency…Why?

2007: CABOTO-S 300-430 for SCENT

2009: CABOTO-S 230-400 for Synchrocyclotron

2010: CABOTO-C 120-400 for K480 SC Cyclotron

Alberto

Degiovanni – TERA Foundation

Slide7

The

CYCLINAC solution7CABOTO-C

120

MeV/u

400

MeV/u

CABOTO-C

components

Source

EBIS - SC

Cyclotron

K

480

-

SC

200

tonsLinac

CCL @ 5.7 GHz18 modules

RF power system

Klystron (P

peak 12 MW)

CArbon

BOoster

for Therapy

in Oncology

CABOTO =

120-400

MeV/u

10/03/2010

Alberto

Degiovanni – TERA Foundation

Slide8

Flexibility

C6+ ions (Q/A=½)EBIS-SC (SuperConducting-Electron Beam Ion Source)

4x108

C

6+

ions (in 3

μs

pulses at

300 Hz

)

10/03/2010

8

Zschornack G. et al, Compact Electron Beam Ion sources / Traps : Review and Prospects, Review of Scientific Instruments 79, 02A703, 2008

Dreebit

Gmbh.

SOURCE

H

2

+

C

6+

Alberto

Degiovanni – TERA Foundation

Slide9

Compactness

10/03/20109

CYCLOTRON

Output

energy: 120 MeV/u

K = 480 superconducting cyclotron

Weight: ~ 200 tons

Saha

S., Superconducting magnet for K-500 cyclotron at VECC, Kolkata, Cryogenics, v. 49 (6), 235-242, 2009

Alberto

Degiovanni – TERA Foundation

Slide10

Modularity

Cell Coupled Linac RF frequency: 5.7 GHz

18 accelerating modules

-

Length

of

each

module

~

1.3

mHigh gradient

: 40 MV/m (

TERA+CLIC collaboration)

10/03/201010CELL COUPLED LINAC

TANK

30

cm

5

cm

HALF CELLS

Alberto

Degiovanni – TERA Foundation

Slide11

Modularity

C-band klystrons (12 MW Peak Power*)Solid State ModulatorsRepetition rate: 200-300 HzPulse length: 4 μ

s

10/03/2010

11

* Toshiba Electron Tubes and Devices Co. LTD.

RF POWER SYSTEM

3 GHz,

Scandinova

C

band

,

5.7

GHz

Alberto

Degiovanni – TERA Foundation

Slide12

18

mod ON17 mod ON

16 mod ON

15

mod

ON

14

mod

ON

Active

Energy

Modulation

+

3D feedback

system

Treatment

of

MOVING

ORGANS

10/03/2010

12

Fast

active

energy

modulation

β

x

(m)

0.403

β

y

(m)

1.493

β

z

(deg/MeV)

32.620

ε

x

(mm

mrad

)

1.5

ε

y

(mm

mrad

)

1.5

ε

z

(deg MeV)

10

Alberto

Degiovanni – TERA Foundation

Slide13

Tumor multipainting

Fast cycling machine(high repetition rate)TumorMULTIPAINTING

10/03/2010

13

Single ‘spot’

pencil beam

Lateral scanning with

magnets: 2 ms/step

3D conformal

treatment

Depth scanning: ACTIVE ENERGY MODULATION

Alberto

Degiovanni – TERA Foundation

Slide14

SUMMARY

First design in C-band for a dual hadron therapy center !CYCLINAC is a competitive

solution

for

hadron

therapy

:

High

Repetition

Rate :

300

Hz

 tumor multipainting

Total power consumption ~ 800 kW

 reduced costsFast active energy modulation  moving organsHigh Accelerating Gradient : 40

MV/m  reduced

size

10/03/2010

14

Alberto

Degiovanni – TERA Foundation

Slide15

Dimensional

comparison among carbon ion accelerators10/03/2010

15

Alberto

Degiovanni – TERA Foundation

Slide16

Output

Energy: 404 MeV/uTotal Length: 23.2 m

n. Klystron:

18

Total

Peak

Power:

170 MW

Module

n. tank

progr

. tank #

n

Acc.Cell

E

S

(

max

surface el. field

)

E

0 (axial el. field)

Energy

Energy gain

Length

progr. Length

Peak Power (13% losses)% used power from klystron

progr. Power (with losses)

Range in water

-

--

-

MV/m

MV/m

MeV/u

MeV/u

m

m

MW

MW

MW

cm

1

3

3

21

181

39.0

133

13.34

1.05

1.05

9.41

0.78

9

4.47

2

3

6

21

180

38.9

147

13.89

1.24

2.29

9.41

0.78

19

5.27

3

3

9

21

180

38.8

162

14.41

1.21

3.50

9.42

0.79

28

6.15

4

3

12

21

179

38.7

177

14.88

1.25

4.75

9.43

0.79

38

7.11

5

3

15

20

183

39.6

191

14.95

1.25

6.00

9.43

0.79

47

8.12

6

3

18

20

182

39.4

207

15.34

1.29

7.29

9.44

0.79

57

9.21

7

3

21

20

182

39.3

223

15.70

1.32

8.62

9.45

0.79

66

10.39

8

3

24

20

181

39.1

239

16.03

1.36

9.98

9.45

0.79

75

11.64

9

3

27

19

184

40.0

254

15.92

1.34

11.32

9.46

0.79

85

12.94

10

3

30

19

183

39.8

271

16.18

1.28

12.60

9.46

0.79

94

14.33

11

3

33

19

182

39.7

287

16.43

1.30

13.90

9.46

0.79

104

15.79

12

3

36

19

180

39.5

304

16.66

1.33

15.23

9.46

0.79

113

17.34

13

3

39

18

183

40.4

320

16.42

1.30

16.53

9.47

0.79

123

18.93

14

3

42

18

182

40.2

337

16.60

1.32

17.85

9.47

0.79

132

20.59

15

3

45

18

180

40.0

354

16.78

1.34

19.19

9.47

0.79

142

22.34

16

3

48

18

178

39.9

370

16.92

1.36

20.55

9.47

0.79

151

24.17

17

3

51

17

181

40.8

387

16.59

1.33

21.88

9.47

0.79

161

26.02183541717940.740416.711.3423.229.480.7917027.95

CABOTO-C high field

10/03/2010

16

Alberto

Degiovanni – TERA Foundation

Slide17

CABOTO-C

low fieldModule

n. tank

progr. tank #

n

Acc.Cell

E

S

(max surface el. field)

E

0

(axial el. field)

Energy

Energy gain

Lengthprogr. LengthPeak Power (13% losses)

% used power from klystron

progr. Power (with losses)

Range in water

-

-

-

-

MV/m

MV/m

MeV/u

MeV/u

m

m

MW

MW

MW

cm

1

4

4

21

149

32.2

135

14.69

1.38

1.38

8.53

0.71

9

4.54

2

4

8

21

149

32.1

150

15.35

1.56

2.94

8.54

0.71

17

5.44

3

4

12

21

148

32.0

166

15.97

1.63

4.57

8.55

0.71

26

6.43

4

4

16

21

148

31.9

183

16.53

1.69

6.26

8.56

0.71

34

7.51

5

4

20

21

147

31.8

200

17.05

1.75

8.01

8.56

0.71

43

8.69

6

4

24

20

150

32.5

217

17.09

1.75

9.75

8.57

0.71

51

9.94

7

4

28

20

149

32.3

234

17.51

1.67

11.43

8.57

0.71

60

11.29

8

4

32

20

148

32.2

252

17.89

1.72

13.15

8.58

0.71

68

12.75

9

4

36

20

147

32.0

270

18.23

1.76

14.91

8.58

0.72

77

14.30

10

4

40

20

146

31.9

289

18.55

1.81

16.72

8.58

0.72

86

15.96

11

4

44

19

148

32.5

307

18.35

1.78

18.49

8.58

0.72

94

17.67

12

4

48

19

147

32.4

326

18.60

1.81

20.30

8.59

0.72

103

19.49

13

4

52

19

145

32.2

345

18.84

1.84

22.15

8.59

0.72

111

21.41

14

4

56

18

148

33.0

363

18.52

1.80

23.95

8.59

0.72

120

23.38

15

4

60

18

146

32.8

382

18.71

1.83

25.78

8.59

0.72

129

25.44

16

4

64

18

144

32.6

401

18.87

1.86

27.64

8.59

0.72

137

27.60

Output

Energy

:

401 MeV/u

Total

Length

:

27.6 m

n. Klystron:

16

Total

Peak

Power:

140 MW

10/03/2010

17

Alberto

Degiovanni – TERA Foundation

Slide18

SUMMARY

First design in C-band for a dual hadron therapy center !CYCLINAC

is a competitive

solution

for

hadron

therapy

:

High

Repetition Rate : 300

Hz  tumor

multipaintingTotal power consumption

~ 800 kW  reduced costsFast active energy modulationHigh Accelerating Gradient : 40 MV/m 

reduced size

Further

developements:Construction

and test

of a small

module in C-band

!

10/03/2010

18

Alberto

Degiovanni – TERA Foundation

Slide19

THANK YOU FOR YOUR ATTENTION