PPT-Approach to thrombocytopenia

jithin P JR1 Medicine introduction P latelets are one of the blood cells that are released from megakaryocytes. Joanna Rupa-Matysek. Hemostatic. System - . general. . information. Normal . hemostatic. system . vessel wall. circulating blood platelets. blood coagulation and . fibrynolysis. Bleeding. . Diathesis. SDPA 2014. Deadwood, SD. Neonatal Thrombocytopenia. Financial Disclosure . I have no relevant financial relationships to disclose.. Objectives. Definition of thrombocytopenia. Understand the pathophysiology of neonatal alloimmune thrombocytopenia. Platelet Counts. Vary with . Age (slight decrease in mean with increased age). Sex (Slightly lower mean in men). Consequences of Misdiagnosis of Inherited Thrombocytopenia. Wrong therapy. Wrong prognosis. (HIT). HEPARIN-INDUCED THROMBOCYTOPENIA. Unfractionated heparin (UFH) (beef > pork). Continuous iv infusion. Cardiopulmonary bypass. Low dose sq. Heparin flushes. Heparin-bonded catheters. Low molecular weight heparin. Articles. by . Ryan Burris, Ali Naqvi, Wendy Yang. Presentation. by . Sam . Lai, Alex . Raufi. Questions. by . Vicki Cheng. Definition. Mild: 100 to 150. Moderate. : 50 to 100. Severe. : < 50. Keep in mind, these are 95% confidence intervals, so 2.5% of population < 150. 5/18/15. Learning Objectives. Understand the mechanisms causing thrombocytopenia. Learn the workup of thrombocytopenia. Understand when to transfuse platelets. Case 1. A 24 year old woman is evaluated for a 1 day history of . limba. . engleza. 2012-2013. Background. 1/3 of all Hematology Consults in a General Hospital are for . thrombocytopenia. 5 to 10% of all hospital patients are thrombocytopenic in the ICU the number increases to 35. 1-vasoconstriction. (thromboxaneA2-Endotheline - . serotonine. ). 2-platelet plug. 3-fibrin formation. 4-fibrinolysis. Primary . hemosthasis. Primary . hemosthasis. : bleeding control by platelet aggregation. 30 September 2019 Pharmaceuticals Creating a global growth platform in haematology In order to utilise the ‘Safe Harbor’ provisions of the United States Private Securities Litigation Reform Ac 1 1 January 2017 Jefferies 2017 London Healthcare Conference 2 2 Disclaimer Certain information contained in this presentation relates to or is based on studies, publications, surveys and other data o 12Postal address SE-11276 Stockholm Sweden Phone 46 8 697 20 00 wwwsobicomPRESS RELEASEStockholm Sweden 12November2019Sobi successfully completesacquisition ofDova PharmaceuticalsSwedish Orphan Biovi Idiopathic Thrombocytopenic PurpuraJune 26 2019May 2019Thrombocytopenia May 21 2018May 2019 2 Drug InformationRegulatory InformationManufacturerDova PharmaceuticalsApplication TypeSupplemental NDAD ARC Jour Volume 4 , Issue 2, 2019, PP 1 - 4 www.arcjournals.org ARC Journal of Hematology Page | 1 Difficulties Diagnostic of Amegacaryocytic Thrombocytopenic Purpura in Developing Country: A Case Dr Briony Cutts and Dr Stefan Kane. Introducing Our Panel..... Professor Beverley Hunt . Obstetric Haematologist. Dr Briony Cutts . Obstetric Haematologist/Obstetric Medicine Physician. Associate Professor Sandra Lowe .