PPT-Approach to thrombocytopenia

jithin P JR1 Medicine introduction P latelets are one of the blood cells that are released from megakaryocytes. The immune mediated form can lead to thrombo sis and the need to consider alternative therapies Types of hepari n related thrombocytopenia HAT Non immune Mediated HIT Immune Mediated Frequency 10 30 1 3 Timing of Onset 4 days Typical 5 10 days Acute Summary of recommendations Patients who are to receive any heparin should have a baseline platelet count 2C Postoperative patients including obstetric cases receiv ing unfractionated heparin UFH should have platelet count monitoring performed every Thrombocytes. Platelets (Thrombocytes). 2- 4 micromillimeters in diameter. 250,000 – 400,000 per microliter . (too few thrombocytopenia – too many thrombocytosis). Lifespan on average 6 – 10 days. Pediatric Diagnosis Paper. Josh Hensley, Ryan Hua, Gary Pearson, and . Johnny Rider. TAR Syndrome. Etiology and Prevalence. TAR syndrome is a genetic disorder which causes an absence of the radius in both . Thrombocytes. Platelets (Thrombocytes). 2- 4 micromillimeters in diameter. 250,000 – 400,000 per microliter . (too few thrombocytopenia – too many thrombocytosis). Lifespan on average 6 – 10 days. Updates . on Management . Muna. . Tahlak. , MD, FACOG. Latifa. Hospital. Objectives. Update on the disease. focus on diagnosis. Complications. timing and mode of delivery . mortality and morbidity . Heather A. Knouff, MSN, RN. Learning Objectives. The learner will be able to explain how DIC, HIT, and ITP develop in the body. The learner will be able to describe manifestations, complications, and diagnostic criteria for DIC, HIT, and ITP. Platelet Counts. Vary with . Age (slight decrease in mean with increased age). Sex (Slightly lower mean in men). Consequences of Misdiagnosis of Inherited Thrombocytopenia. Wrong therapy. Wrong prognosis. (HIT). HEPARIN-INDUCED THROMBOCYTOPENIA. Unfractionated heparin (UFH) (beef > pork). Continuous iv infusion. Cardiopulmonary bypass. Low dose sq. Heparin flushes. Heparin-bonded catheters. Low molecular weight heparin. R. Campbell Garland, PGY-2. Overview. Review of normal platelet life cycle. Definition of thrombocytopenia. Mechanisms of thrombocytopenia. Production, destruction, sequestration. Outpatient a. pproach . Introduction. Epidemiology . Drug-induced Aplastic anemia. Drug-induced Hemolytic anemia. Drug-induced Neutropenia and Agranulocytosis. Drug-induced Thrombocytopenia. Drug-induced Megaloblastic anemia. 1-vasoconstriction. (thromboxaneA2-Endotheline - . serotonine. ). 2-platelet plug. 3-fibrin formation. 4-fibrinolysis. Primary . hemosthasis. Primary . hemosthasis. : bleeding control by platelet aggregation. Idiopathic Thrombocytopenic PurpuraJune 26 2019May 2019Thrombocytopenia May 21 2018May 2019 2 Drug InformationRegulatory InformationManufacturerDova PharmaceuticalsApplication TypeSupplemental NDAD Charlotte A. Bradbury. , . Julie . Pell. Published in . nejm. on 02 . sep. 2021 . INTRODUCTION . Immune thrombocytopenia is a . rare condition. , with an incidence . in . . adults . of . 2.9 per .