PPT-Platelet

Thrombocytes Platelets Thrombocytes 2 4 micromillimeters in diameter 250000 400000 per microliter too few thrombocytopenia too many thrombocytosis Lifespan on average 6 10 days. Abstract. Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura is thought to be due to autoimmune disease. An abnormal autoantibody (immunoglobulin G) binds to the platelet membrane, causing removal by the spleen. If left untreated it could lead to bleeding and possibly death (. to Platelet Serotonin. Platelet. -rich plasma. Expected fixed platelet count. Unstable ACS environment. Potential. confounders. Off-site laboratory processing→. delayed time to processing. Platelet Serotonin Laboratory Protocol. Morey A. Blinder, M.D.. Associate Professor of Medicine. and Pathology & Immunology. Objectives. Coagulation factor disorders and treatment. Disorders of platelets and platelet transfusion. Adjunctive drug therapy for bleeding. 244much helpful. Incubation of sample with EDTA andcalculating the difference in MPV before and afteraddition of EDTA, known as dMPV, is found to be morereflective of PSL than MPV alone6. Similarly, d Dr. S. Parthasarathy . MD., DA., DNB, MD (. Acu. ), Dip. . Diab. . DCA, Dip. Software statistics, PhD(physiology). Mahatma Gandhi Medical College and Research Institute, . Puducherry. , India . Definition . Platelets aggregation. Studying Platelets Disorders. . Numbers. . CBC. PLT count. PLT morphology. Function. . Bleeding . Time (BT). Platelet Aggregation. Whole blood aggregation . Platelet-rich plasma aggregation. Cangrelor. . on . Platelet P2Y. 12. Receptor . Mediated Signaling . in . Prasugrel. Treated Patients. Fabiana Rollini, . Francesco Franchi, . Antonio . Tello-Montoliu, Ronakkumar Patel, Andrew Darlington, . Abishek Santhakumar, PhD. Lecturer & Course-coordinator - Pathology. School of Medical and Applied Sciences. Overview . . Introduction. Platelet activity & Thrombosis. Aim. Methodology. Study overview. SDPA 2014. Deadwood, SD. Neonatal Thrombocytopenia. Financial Disclosure . I have no relevant financial relationships to disclose.. Objectives. Definition of thrombocytopenia. Understand the pathophysiology of neonatal alloimmune thrombocytopenia. Platelet Counts. Vary with . Age (slight decrease in mean with increased age). Sex (Slightly lower mean in men). Consequences of Misdiagnosis of Inherited Thrombocytopenia. Wrong therapy. Wrong prognosis. Autoimmune (ITP). Childhood. Adult. Drug-induced. Heparin. Quinine, others. Immune complex (infection, etc). Alloimmune. Post-transfusion purpura. Neonatal purpura. ITP. Childhood ITP (most < 10 . R. Campbell Garland, PGY-2. Overview. Review of normal platelet life cycle. Definition of thrombocytopenia. Mechanisms of thrombocytopenia. Production, destruction, sequestration. Outpatient a. pproach . Practical Hematology Lab. - LAB . -. Platelet . Satellitism. Morphology. Platelets clumped around neutrophils. .. Found . in. EDTA in vitro induced change of no clinical significance except false low platelet count (in vitro).. Platelets are the smallest formed elements in the blood, normally ranging in size from 2-4 microns. . Platelets function in the coagulation of blood.. A normal platelet count is 150,000-400,000/c.mm.in human .