PPT-CAR T Cells in non-Hodgkin lymphoma (NHL)

Jean Koff MD MSc July 20 2023 disclosures Research funding Oncternal Therapeutics Viracta Therapeutics Atara Biotherapeutics Consulting fees Janssen Pharmacyclics MorphoSys. Rob Corbett. NCCN. Christchurch. Hodgkin Lymphoma. Great success story!. LMIC. >50% 0-10yrs old. Striking male predominance. Symptoms. 60% < 6months. B symptoms 40%. Wt. loss. Fever. Night sweats. and their . precursor . cells. .  The name often refers to just the . cancerous. . ones . rather than all such . tumors. .. Many lymphomas are known to be due to specific genetic mutations.. 3. rd. ymphoma. Sobia Ozair. March 8, 2017. MD Anderson Lecture Series. Indolent NHL include:. Follicular. CLL/SLL. Marginal . zone. Cutaneous T-cell. Anaplastic Large Cell . Lymphoma. Follicular NHL. Most . Jonathon B. Cohen, MD. Dept of . Hematology. /Medical Oncology. Co-Director . Lymphoma Program. Relapsed aggressive . nhl. associated with shortened survival. Scholar-1 (Crump et al, Blood 2017). Martin et al, Blood 2016. lecture 3. Lecturer . Dr.Mohanad Al-Hindawi. MBCHB, MSc. Histopathology, . CABHS.Anatomical. pathology. Non-Hodgkin lymphoma-Clinical . features . Two thirds of NHLs and . (virtually all Hodgkin lymphomas) . Basics. Lymphoma – a cancer started in the cells of the immune system. 5 types:. Hodgkin Disease. Non-Hodgkin Lymphoma. Non-Hodgkin Lymphoma in Children. Lymphoma of the Skin. Waldenstrom. . Macroglobulinemia. MODERATOR : DR. GANAPULE . Definition . Lymphomas are malignant . tumours. of lymphoid tissue which give rise to solid tissue masses.. Heterogenous. group of disorders.. HODGKINS LYMPHOMA. NON-HODGKINS. How to cite: Kusminsky G, Abriata G, Forman D, Sierra MS (2016).Etiology of Hodgkin lymphoma (C81) in Central and South America.In: Cancer in Central and South America.Lyon: International Agency for What is Non-Hodgkin lymphoma? CANCER CARE Lymph nodes Lymphoma refers to a group of cancers that come from a specic group of white blood cells inside your body. ese cells are called lymph L, FILIPPAP, MOWAN. Primary nasal paranasaloropharyngeal lymphoma in the pediatric agegroup. Cancer 1990; 65: 1438-1444.YP, SYW,XF, ZXH, LRadiotherapy As Primary Treatment for stage IEand IIE nasal na Overview Case 3 • 59 year old man with lymphadenopathy in the neck, supraclavicular area, inguinal area . He states that he has had LN for at least 18 months and they have waxed and waned . Dr. Sanne Lugthart. (. Dr. Stephen Robinson). University Hospital Bristol. 20 June 2019. Scope Of Talk. Current CAR T products available for NHS patients. The CAR T pathway (up to re-infusion). Patients Cases. Noticed lump in right groin (Sept 2014). Painless. Nil inflammation or . discolourations. Nil associated symptoms. U/S guided core biopsy with GP (Oct 2014). 17x13x21mm lymph node, slightly . hypervascular. lymph nodes . Tonsils and adenoids (Waldeyer's ring) . Peyer's patches and appendix . White pulp of the spleen . Lymphadenopathy :. Localized (e.g., infection) or generalized (Systemic disease). . May be due to inflammatory, reactive or neoplastic disorders.