PPT-ROLE OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND ANGIOTENSIN RECEPTOR BLOCKERS

IN TYPE I DIABETIC NEPHROPATHY DRNASIM MUSA Type I IDDM is characterized by The abrupt onset of symptoms Insulinopenia Dependence on injected insulin for life Proneness to ketoacidosis . Drugs Acting on the Renin-Angiotensin-Aldosterone System. Physiology of the renin-angiotensin-aldosterone system. Angiotensin-converting enzyme inhibitors. Angiotensin II receptor blockers. Aldosterone antagonists. Dr. . Naser. Ashraf . Department of Basic Medical Sciences . College of Medicine . Majmaah University . Objectives . List major drug groups used in treatment of heart failure . Explain mechanism of action of digitalis and its major effects . MARLON T. CO,MD. DISCLOSURE. Advisory board of Merck Philippines. Ps-DZ, 2009. Global Leading Risks for Death, 2010. Systolic blood pressure > 115 mmHg. Global Burden of Disease Study 2010 , . Lancet . Blockers. :. Impact on Adverse Outcomes in Hospitalized Patients . with Severe Acute Respiratory Distress Syndrome Coronavirus 2 (SARS-CoV-2). THE BRACE CORONA TRIAL. Renato D. Lopes, MD, PhD. on behalf of the BRACE CORONA Investigators. Dr.AZDAKI. . (cardiologist).  Initial . monotherapy. is successful in many patients with mild primary hypertension (formerly called "essential" hypertension). . However, single-drug therapy is unlikely to attain goal blood pressure in patients whose blood pressures are more than 20/10 mmHg above goal. . as antagonists . for AT. 2. . receptors to decrease . bradykinin. production . Tina . Stutzman. Nick Swenson. 20.109. May 12, 2010. Hypertension is related to renal and cardiac . f. ailure . Hypertension (high blood pressure). ACEIs are among the most widely prescribed antihypertensive drugs. .. In general, these . drugs are . well absorbed from the GI tract, reaching peak . serum conc. within . 1 to 4 hours. . These drugs are . Assistant lecturer Ola . N. assr. 12 Nov 2015 MSc Clinical Pharmacy . Aim and objectives. By the end of the session, the students will be able to:. Know indications, side effects, contraindications, doses and drug interactions of all drugs mentioned in the list.. System. The Cardiovascular Continuum . Myocardial Infarction. Heart Failure. End-Stage Heart Disease. Plaque Rupture. Risk Factors. Hypertension. Hyperlipidemia. Diabetes. Atherosclerosis. Endothelial Dysfunction. enzyme inhibitors (ACE inhibitors). inhibit the conversion of angiotensin I to angiotensin II.. The. . main . indications of ACE inhibitors are shown below.. Heart Failure. ACE inhibitors are used in all grades of heart failure, . W. Hinton. 1,2. , H. Dambha-Miller. 3. , M.Feher. 1. , J. Sheppard. 1. , M.Joy. 1. , N. Munro. 2,4. , . S. de Lusignan. 1,5. 1 Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK. BP. Congest-ion*. Haemo. -globin. K. +. GFR. BNP#. Echo. Diuretics. . . . . . . . ACEi/ARB. . . . I. ARNI. . . . I. I. β. -Blocker. R?. . R?. . I. MRA. . when resting systolic blood pressure exceeds . 130 or diastolic . blood pressure exceeds 80 mm . Hg.. Even stage 1 hypertension (<140/90. ) has been reported to increase the risk of end-organ damage. Converting. . Enzyme. . Inhibitors. . or . Angiotensin. . Receptor. . Blockers. . Use and. . Covid-. 19. . Infection . Among. . Patients with. . Hypertension. Jaejin. . An. ,. . Rong. . Wei,.