PPT-Figure 4 Figure 4. A) Comparison of partial M-gene nucleotide sequences of Siliguri

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Chadha M Comer JA Lowe L Rota PA Rollin PE Bellini WJ et al Nipah Virusassociated Encephalitis Outbreak Siliguri India Emerg Infect Dis 2006122235240 httpsdoiorg103201eid1202051247

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Figure 4 Figure 4. A) Comparison of partial M-gene nucleotide sequences of Siliguri: Transcript


Chadha M Comer JA Lowe L Rota PA Rollin PE Bellini WJ et al Nipah Virusassociated Encephalitis Outbreak Siliguri India Emerg Infect Dis 2006122235240 httpsdoiorg103201eid1202051247. Basic Local Alignment Search Tool. (Altschul et al. 1990. ). What is blast. ?. BLAST .  DNA/protein databases. GOOGLE  internet. . D. Fristrom, Boston U. .. Uses for Blast. . Identifying unknown sequence. 2. Terminology . Genome. – entire genetic material of an individual. Transcriptome. – set of transcribed sequences. Proteome. – set of proteins encoded by the genome. . Gene. * Basic . physical and functional units of heredity.. Simões RO, Monteiro FA, Sánchez E, Thiengo SC, Garcia JS, Costa-Neto SF, et al. Endemic Angiostrongyliasis, Rio de Janeiro, Brazil. Emerg Infect Dis. 2011;17(7):1331-1333. https://doi.org/10.3201/eid1707.101822. Evolution occurs through a set of modifications to the DNA. These modifications include point mutations, insertions, deletions, and rearrangements. Seemingly diverse species (say mice and humans) share significant similarity (80-90%) in their genes. What if it’s NOT just the number?. Gene Mutations. Damaged Chromosomes . –. sometimes a portion of a gene or chromosome is lost or damaged during meiosis. Gene mutation. – a mutation that affects the gene. Petrucca A, Cipriani P, Sessa R, Teggi A, Pustorino R, Santapaola D, et al. Burkholderia cenocepacia Vaginal Infection in Patient with Smoldering Myeloma and Chronic Hepatitis C. Emerg Infect Dis. 2004;10(11):1957-1959. https://doi.org/10.3201/eid1011.040127. Huong VT, Yoshimatsu K, Luan VD, Van Tuan L, Nhi L, Arikawa J, et al. Hemorrhagic Fever with Renal Syndrome, Vietnam. Emerg Infect Dis. 2010;16(2):363-365. https://doi.org/10.3201/eid1602.091204. Tappe D, Meyer M, Oesterlein A, Jaye A, Frosch M, Schoen C, et al. Transmission of Armillifer armillatus Ova at Snake Farm, The Gambia, West Africa. Emerg Infect Dis. 2011;17(2):251-254. https://doi.org/10.3201/eid1702.101118. Fischer TK, Midgley S, Dalgaard C, Nielsen AY. Human Parechovirus Infection, Denmark. Emerg Infect Dis. 2014;20(1):83-87. https://doi.org/10.3201/eid2001.130569. Megid J, Borges IA, Abrahão JS, Trindade GS, Appolinário CM, Ribeiro MG, et al. Vaccinia Virus Zoonotic Infection, São Paulo State, Brazil. Emerg Infect Dis. 2012;18(1):189-191. https://doi.org/10.3201/eid1801.110692. Bessaud M, Peyrefitte CN, Pastorino BA, Tock F, Merle O, Colpart J, et al. Chikungunya Virus Strains, Reunion Island Outbreak. Emerg Infect Dis. 2006;12(10):1604-1605. https://doi.org/10.3201/eid1210.060596. Wylie KM, Wylie TN, Orvedahl A, Buller RS, Herter BN, Magrini V, et al. Genome Sequence of Enterovirus D68 from St. Louis, Missouri, USA. Emerg Infect Dis. 2015;21(1):184-186. https://doi.org/10.3201/eid2101.141605. Galeno H, Mora J, Villagra E, Fernandez J, Hernandez J, Mertz GJ, et al. First Human Isolate of Hantavirus (Andes virus) in the Americas. Emerg Infect Dis. 2002;8(7):657-661. https://doi.org/10.3201/eid0807.010277. Khetsuriani N, Lu X, Teague WG, Kazerouni N, Anderson LJ, Erdman DD. Novel Human Rhinoviruses and Exacerbation of Asthma in Children. Emerg Infect Dis. 2008;14(11):1793-1796. https://doi.org/10.3201/eid1411.080386.

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