PDF-Overstretching B-DNA: The Elastic Response of Individual Double-Strand

When F 65 pN Fig 2 the molecule suddenly yields lengthens and eventually overstretches to 17 times its Bform con cause the biotinstreptavidin bond often breaks after a few seconds at this. The cell has reached the interphase of its cell cycle. DNA is now in the form of identical sister chromatids. The double helix untwists. Hydrogen bonds start to break which ‘unzips’ the DNA. The bases on each strand are now exposed. PROMOTER REGION. REGION. RNA POLYMERASE. POLYMERASE. =. WRITER. S Phase:. Synthesis of DNA. DNA REPLICATION. DNA IS REPLICATED IN A. SEMI-CONSERVATIVE. MANNER. In DNA Replication, the entire genome doubles;. Chapter . 7.2. Processing of Genetic Material. What is DNA Replication. The process by which the DNA within a cell makes exact copies of itself. Balance of speed and accuracy. Used for growth, repair and embryonic development. Objective: . To determine how traits are passed from parent to offspring . Bell work: . In what organelle do we find the instructions for our traits? . Nucleus. What are those instructions called?. DNA: Deoxyribonucleic acid. Objectives:. 1. Summarize the roles of the different enzymes involved in replication of DNA.. 2. Explain how the leading and lagging strands are replicated differently . Semiconservative. Replication. shapes and patterns. 조연우. Contents. DNA. DNA origami. The application of DNA origami. DNA origami structure. “Normal DNA”. 이중나선 형태로 존재. Double Stranded, Double Helix. Adenine, Thymine, Guanine, Cytosine . DNA Replication. Protein Synthesis. Transcription. Translation. Cell Cycle. 1928 – Griffith. 1944 – Avery, McCarty, & . McCleod. Bacteriophage. Viruses that attack bacterial cells (“bacteria eaters”). DNA damage DNA gets damaged a lot ! DNA damage DNA gets damaged a lot! >200,000 events/human cell/day DNA damage Occurs 2 ways 1) spontaneously 2) mutagens : damage DNA Transposons Discovered by Barbara McClintock DNA – Deoxyribonucleic Acid. Found in the nucleus of Eukaryotic Cells. . mostly found loose in the form of chromatin. . during mitosis condenses into chromosomes. Size of Genetic Material. Genome. In . their 1953 announcement of a double helix structure for DNA, Watson and Crick stated, . "It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.". th. period. DNA means deoxyribonucleic acid . early 1900’s—not thought very important because so simple. DNA is inherited from your parents—basis for genetics . discovered in 1940’s. Mutations mess up DNA & can cause birth defects or diseases . Mitochondrial DNA replication. MtDNA. replication is not directly linked to the plant cell cycle, and . mtDNA. copy numbers can vary widely depending on the tissue and stage of development.. MtDNA. complementary. base . pairs.. Learning Goal . Describe the double helix of DNA.. DNA, Ratio of Bases. Scientists determined that . adenine is paired (1:1) with thymine.. guanine is paired (1:1) with cytosine. . . What is DNA?. DNA is a . Nucleic Acid in the nucleus. Polymer of . Nucleotides. Each nucleotide consists of. Deoxy. ribose (5-carbon sugar) . Phosphate group. a nitrogen-containing base. Four bases.