Objectives List significant healthcare associated infections Understand the epidemiology of significant healthcare associated infections Identify disease transmission Utilizing evidence based literature develop strategies used to prevent the spread of infection ID: 734837
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Slide1
Prepared Nurses Protect Patients: Prevention Strategies for Healthcare-Associated Infections and Emerging Infectious Diseases Slide2
Objectives
List significant healthcare associated infections
Understand the epidemiology of significant healthcare associated infections
Identify disease transmission Utilizing evidence based literature develop strategies used to prevent the spread of infectionSlide3
Healthcare-associated Infection (HAI)
An infection that
patients acquire during the course of receiving treatment for other conditions within a
healthcare setting Slide4
Common type of HAIs include:
Catheter-associated
urinary tract
infectionsCentral-line associated bloodstream infectionsSurgical site infectionsMethicillin Resistant Staphylococcus aureus (MRSA)
Clostridium difficileSlide5
Other infections: Old and New
Tuberculosis
Human Immunodeficiency Virus (HIV)
Candida aurisZIKASlide6
HAIs in the U.S.
1 out of
25
hospitalized patientsIncreased morbidity and mortality Increase in length of hospitalization
Attributed
costs: $26-33 billion
annually
Impact the patient and familySlide7
Germs spread
within and across health care
facilitiesSlide8
National Healthcare Safety Network (NHSN)Slide9
HAI Progress ReportsSlide10
HAI Progress ReportsSlide11
Value Based PurchasingSlide12
Type of HAIs and Prevention StrategiesSlide13
Type of HAIs and Prevention Strategies
Catheter associated urinary tract infections
(CA UTIs)
Central line associated bloodstream infections
(CLA-BSI)
Surgical Site infections
(SSIs)
C.difficile
MRSA (blood)Slide14
Catheter associated urinary tract infections (CA UTIs)
Symptomatic UTI (SUTI)
Indwelling urinary catheter in place > 2 days on the date of event
AND
present for any portion of the day on the day of event
OR
removed the day before the event.
Patient has at least one of the following: fever >100.4, suprapubic tenderness, costovertebral angle pain or tenderness, urinary urgency, urinary frequency, dysuria
Patient has a urine culture with no more than 2 species identified, at least one of which is a bacterium of
>
100,000 CFUsSlide15
Catheter associated urinary tract infections
(CA UTIs
)
Prevention
Insert catheter using established indications:
Acute
urinary retention
:
e.g
., due to medication
, anesthesia
,
paralytics
Acute
bladder outlet obstruction
: e.g., due to severe prostate
enlargement
Need for
accurate measurements of urinary output in the critically ill
To assist in healing of
open sacral or perineal wounds in incontinent patients
To improve comfort for end of
life
Patient requires strict prolonged immobilization
(e.g
.,
multiple traumatic
injuries)
Selected peri-operative
needs
Slide16
Catheter associated urinary tract infections
(CA UTIs
)
Prevention
Insert under aseptic technique, using staff members
Secure catheter to leg
Drainage bag is below the level of the bladder to prevent backflow
Tubing is not kinked
Label drainage bag with insertion date/time
Assess the need for the catheter q shift
Perform hand hygiene prior to handling the catheter and after
Obtain specimens using sterile technique
Separate emptying container
Educate the patient and family on the prevention of CA UTIsSlide17
Central line associated bloodstream infections
(CLA BSIs)
Lab-Confirmed Bloodstream Infection
Patient has at least one of the following: fever > 100.4F, chills or hypotension
AND
Organism9S0 identify from blood is not related to an infection at another site Slide18
Central line associated bloodstream infections (CLA BSIs)
Prevention Measures:
Insert the catheter under maximal barrier protection using aseptic technique
Gown, gloves, mask, large drape
Use alcohol impregnated caps
Use endcaps when disconnecting the catheter from tubing
Label IV tubing with date/time/ initials
Change IV tubing and dressing per hospital policy
Assess the need for the catheter q shift
Educate the patient and family on the prevention of CLA BSIsSlide19
Surgical Site Infections
(SSIs)
Focus:
Colon procedures
Total Abdominal Hysterectomies (TAH)
Total Knee Replacements (TKR)
Coronary Artery Bypass Graphs (CABG)Slide20
Surgical Site Infections
(SSIs)
Prevention
Preoperative:
Smoking and alcohol cessation, dental care, blood sugar control, no remote sites of infection, discontinuation of certain medications
MRSA/MSSA screening
CHG baths
Correct antibiotic
Patient and family educationSlide21
Surgical Site Infections (SSIs) Prevention
Intraoperative:
Timing of antibiotics
Redosing antibiotics
Supplemental oxygen
Normothermia
Type of anesthesia
Changing gloves at certain timesSlide22
Surgical Site Infections (SSIs) Prevention
Postoperative:
Stopping antibiotics
Change dressing per hospital policy
Ambulate
Discontinue indwelling urinary catheter
Discharge home
Educate the patient and family on infection preventionSlide23
Clostridium difficile
Risk Factors:
Age
Previous exposure to health care
Previous roommate’s status
Antibiotics
Proton Pump Inhibitors (PPIs)
Diabetes
Dialysis
ResidenceSlide24
Clostridium difficile
Microbiology –
Clostridium
difficile
is an anaerobic gram-positive, spore-forming, toxin-producing bacillus
and is the cause for
C.difficile
associated diarrhea.
Epidemiology –
There
has been dramatic change in the epidemiology of Clostridium difficile infection (CDI) since the turn of the 21st
century including an
increase in incidence and
severity
, occurring at a disproportionately higher frequency
in
older patients.Slide25
Clostridium difficile
Reporting definition –
specimen collected > 3 days after admission to the facility
Colonization data -
Prevalence of asymptomatic
C. difficile c
olonization among elderly residents ranged from 0 to 51 %, possibly because CDI is often endemic in units or institutions with elderly patientsSlide26
Clostridium difficile
Symptoms
Diarrhea
Elevated WBC’s
Temperature
Abdominal painSlide27
Clostridium difficile
Prevention
Isolation
Hand Hygiene
Antibiotic Stewardship
Clean environment
Clean patient care equipment
Fecal transplant to prevent recurrenceSlide28
Methicillin Resistant Staphylococcus aureus
(MRSA)
Microbiology
–
gram positive cocci resistant to oxacillin
Epidemiology
–
The
frequency of methicillin-resistant
Staphylococcus aureus
(MRSA) infections continues to grow in hospital-associated settings and, more recently, in community settings in the United States and globally.Slide29
Methicillin Resistant Staphylococcus aureus (MRSA)Slide30
Methicillin Resistant Staphylococcus aureus
(MRSA)
Reporting Definition
-
S
pecimen
collected > 3 days after admission to the facility
Colonization data
–
About
one-third of the general population carry staphylococcal microbes.
Estimates
of healthcare workers’ carrier status range from 50% to 90
%.
Slide31
Methicillin Resistant Staphylococcus aureus
(MRSA)
Risk Factors
Diabetes,
Residence prior to admission
Participation in group activities/sports
SymptomsSlide32
Methicillin Resistant Staphylococcus aureus
(MRSA
)
Prevention
Isolation
Hand hygiene
Antibiotic Stewardship – Vancomycin time out
Clean environment
Clean patient care equipment
DecolonizationSlide33
Old and New InfectionsSlide34
Tuberculosis
Epidemiology –
T
he
TB epidemic is larger than previously
estimated
The
number of TB deaths and the TB incidence rate continue to fall
globally.
In
2015, there were an estimated 10.4 million new (incident) TB cases worldwide
, of which
5.9
million (56%) were among men
,
3.5 million (34%) among women
and
1.0 million (10%) among children.
People
living with HIV accounted for 1.2 million (11%) of all new TB cases.
Six
countries accounted for 60% of the new cases: India, Indonesia, China, Nigeria, Pakistan and South Africa
. Slide35
Tuberculosis
Risk Factors
Age
Foreign born
Immunosuppression
Exposure
Symptoms
Cough
Fever
Chills
Night sweats
HemoptysisSlide36
Tuberculosis - Prevention
Early Identification
Early Isolation
Airborne precautions – negative pressure room
Personnel protective equipmentSlide37
Human Immunodeficiency Virus
(HIV)
Epidemiology
The
epidemiology of
HIV in
the United States has changed significantly from the early 1980s when it began as an epidemic predominantly in young, white, middle-class men who have sex with men (MSM) and who resided principally in a few of the larger West and East Coast cities
.
Today
,
HIV is
a disease of
a greater
demographic diversity, affecting all ages, sexes, races, and income levels; involving multiple transmission risk behaviors; and having a broad geographic distribution in the United States
.
This epidemiologic diversity is important to understand in order to target the interventions needed to diagnose and treat this disease and to potentially slow the transmission of the virus. Slide38
Human Immunodeficiency Virus
(HIV)
Risk Factors
Unprotected sex
IVDU
Other
Symptoms
Weight loss
Fevers
Diarrhea
Rash
STIsSlide39
HIV - Care
No isolation if respiratory symptoms are absent
Continue antiretroviral therapy
Educate patient on transmission of virus
toothbrush, razors
unprotected sex
PRepSlide40
Principles of Disease TransmissionSlide41
Infection vs. Colonization
I
nfection
Occurs when pathogens and other microorganisms
are
present in the body and cause tissue damage and signs and symptoms of illness
(e.g.,
fever, redness, pain).
Colonization
Occurs
w
hen pathogens and other
mi
croorganisms
are present but do not
cause signs and symptoms of illness. Slide42
Incubation Period
People are not immediately infectious after
exposure
The
period
between exposure to an infection and the appearance of the first symptoms
Can vary by individual
, degree
of exposure and type of
microorganismSlide43
Chain of InfectionSlide44
Modes of Transmission
Three main categories:
Contact
Droplet
AirborneSlide45
Modes of Transmission
Contact Transmission
Direct transmission -
microorganisms transferred from one infected person to another person without a contaminated intermediate object or person
Indirect transmission -
transfer of an infectious agent through a contaminated intermediate object or
person
Droplet Transmission-
Transmission of pathogens spread through close respiratory or mucous membrane contact with respiratory
secretions, e.g., group A strep
Airborne Transmission -
Transmission of infectious agents that remain infectious over long distances when suspended in the
air, e.g., tuberculosis, varicellaSlide46
Prevention StrategiesSlide47
Hand Hygiene
Hand
Hygiene:
The single most important strategy in the prevention of infections.
Use
of soap/water or alcohol-based
hand sanitizer
Before direct patient contact
After contact with bodily fluids or excretions, (non-) intact skin
Between body sites on the same patient
After contact with fomites proximal to patient
Before and after
removing glovesSlide48
Hand Hygiene
Access to hand hygiene
stations is essential
Wash hand for 15 seconds
Barriers to effective hand hygieneSlide49
Standard Precautions
Standard Precautions – all patients blood and body fluids are potentially infectious
Recommended care of all patients regardless of suspected or confirmed infection
Application depends on the nature of healthcare personnel – patient interaction and anticipated exposure to blood / body fluids or known infectious agentsSlide50
Standard Precautions
Key Elements
Hand
hygiene
P
ersonal
protective
equipment
Safe
injection
practices
Safe
handling of potentially contaminated
equipment, environmental surfaces, and linen
Respiratory hygiene/cough etiquetteSlide51
Standard PrecautionsPersonal Protective Equipment
Wear
PPE appropriate to anticipated patient
interaction
Gloves, gown, face protection (masks, goggles, face shields), respiratory protection
Prevent
contamination of clothing and skin during
PPE
removal
Remove and discard PPE before leaving patient room/cubicle
Do not reuse disposable
PPE Slide52
Standard PrecautionsRespiratory Hygiene and Cough Etiquette
Prevention strategies include:
Posting signs at
entrancesProviding tissues and no-touch receptacles for disposal
Providing resources for hand hygiene
Offering facemasks to coughing patients and other symptomatic individuals upon entry to the facility
Providing space and encouraging persons with symptoms of respiratory infections to sit as far away from others as possibleSlide53
Standard Precautions
Injection Safety
Unsafe practices that have led to patient harm include:
Failure to use aseptic technique when preparing or administering
medications
Use of the same syringe (with or without the same needle) to administer medication to >1 patient
Reuse of a syringe (with or without the same needle) to access a medication container used for >1 patient
Use of medications labeled as single-dose or single-use for >1 patientSlide54
Standard PrecautionsInjection Safe Practices
Never administer medications from the same syringe to more than on patient, even if the needle has been change
Do not enter a vial with a used syringe or
needleMedications packaged as single-use vials never be used
for more than one
patient
Bags or bottles of intravenous solution not be used as a common source of supply for more than one
patient
Cleanse the access diaphragm of medication vials before inserting a device into the vialSlide55
Standard PrecautionsInjection Safe Practices
Ensure medication containers labeled as single-dose or single-use are used for one patient only
Dedicate
multi-dose vials to a single patient whenever possibleIf multi-dose vials are used for >1 patient, restrict the vials to a centralized medication area and do not bring them into patient treatment areas (e.g., operating room, patient room/cubicle)
Dispose of used sharps at the point of use in a sharps container that is closable, puncture-resistant and leak-proofSlide56
Standard PrecautionsLinen and Laundry
Handle used linen with minimum agitation to avoid contamination of air, surfaces, and persons
Always use Standard Precautions when handling soiled laundrySlide57
Standard PrecautionsEnvironmental Cleaning
Inadequate
environmental cleaning and disinfection practices have led to the transmission of
healthcare-acquired pathogens related to contamination of near-patient surfaces and equipmentFollow
manufacturer’s recommendations for use of cleaners and EPA-registered disinfectants
(know the
contact
time,)Slide58
Standard PrecautionsInstrument Reprocessing
Ensure that reusable medical equipment
(e.g., point-of-care devices, surgical instruments, endoscopes) is cleaned and reprocessed appropriately prior to use on another
patientIf the manufacturer instructions are not provided, the device may not be suitable for multi-patient use
Follow manufacturer’s instructions for proper reprocessing
Assign
responsibilities for reprocessing of medical equipment to healthcare personnel with appropriate trainingSlide59
Transmission-Based Precautions
Used in addition to Standard Precautions
Contact
Airborne
Droplet Slide60
Contact Isolation
For infections spread by direct or indirect contact with patients or patient-care environment (e.g.,
MRSA,
VRE)
Private
room or room shared with patients with the same infection
status
Wear disposable gown and gloves when entering the patient
room
Remove disposable
gown and gloves
and
discarded inside the patient
room
Wash hands immediately after leaving the patient
room
Clean patient room daily using a hospital disinfectant, with attention to frequently touched
surfaces
Use dedicated equipment if possible (e.g., stethoscopesSlide61
Droplet Transmission
For infections spread by
splashes generated
by coughs, sneezes, etc. (e.g.,
meningitis
, pertussis,
seasonal influenza)
Patients
should be placed in single-patient room
PPE: Eye protection and
a
mask (facemask, N-95, etc.), or face shield
are worn to prevent droplets reaching the mucous membranes of the eyes, nose and
mouth upon room entry or within 6 feet of the patient
Patient
should wear a surgical mask when outside of the patient
roomSlide62
Airborne Precautions
For
infections spread by particles that remain
viable and suspended in
the air (TB, measles,
chickenpox,
and
smallpox)
Patient should be placed in negative pressure (
a
irborne isolation) room
PPE: N-95 or higher respirator for personnel inside isolation room
Patient should wear a surgical mask when outside of the patient roomSlide63
PracticeSlide64
Exercise 1: Disease Transmission
A 35 year old patient on hospice develops a cough, fever, and pancytopenia three weeks after admission.
C
ultures reveal Aspergillus.
Who is the host?
What is the agent?
What are possible environments sources/reservoirs?Slide65
Exercise 1: Disease Transmission
35 year old patient on hospice develops a cough, fever, and pancytopenia three weeks after admission.
C
ultures reveal Aspergillus.
Host: Immunocompromised patient
Agent: Aspergillus
Potential environmental sources:
Construction
, ventilation systemSlide66
Exercise 2: Reservoirs
Your patient is a 84 year old woman admitted to your telemetry unit for a wound infection caused by group A streptococcus (GAS). She lives in a nursing home and receives only enteral feedings.
She has chronic hepatitis B,
C. difficile, diabetes, is incontinent and has dementia.
What potential environmental sources/reservoirs of infection exist in this situation?Slide67
Exercise 2: Reservoirs
Your patient is a 84 year old woman admitted to your telemetry unit for a wound infection caused by group A streptococcus (GAS). She lives in a nursing home and receives only enteral feedings. She has chronic hepatitis B,
C. difficile
, diabetes, is incontinent and has dementia.
Potential Reservoirs
Hepatitis B-patient’s blood and other body fluids, used lancet, insulin syringe and vial, dried blood on glucometer, contaminated gloves
Group A Streptococcus-
Intact
skin, sheets, bed rails, HCW hands
C. diff- surfaces
; spores on counter tops and not
killed, HCW hands, diapers, telemetry equipmentSlide68
Exercise 3: PPE
You are the primary nurse for a 45 year male that suffered a spinal cord injury. He is
quadriplegic
and now has multiple decubiti. Upon your assessment, you note that he has a large, unstageable sacral decubitus that has foul-smelling, copious drainage. As you prepare for his wound
care
(at a minimum
)
what PPE should you anticipate using?
Gown
Gloves
G
loves
only
A
&
B
No
PPE requiredSlide69
Exercise 3: PPE
You are the primary nurse for a 45 year male that suffered a spinal cord injury. He is
quadriplegic
and now has multiple decubiti. Upon your assessment, you note that he has a large, unstageable sacral decubitus that has foul-smelling, copious drainage. As you prepare for his wound
care
(at a minimum
)
what PPE should you anticipate using?
Gown
Gloves
G
loves
only
A
&
B
No
PPE requiredSlide70
Emerging DiseasesSlide71
Candida auris
Fungus resistant to common antifungals
Causes severe infections and invasive disease
33 cases in four states identified since 2013; all but one case was identified between 2015-201760% mortality rate
Infections identified in blood, wound, ear; isolated in respiratory tract and urineSlide72
Candida auris
Risk factors include recent surgery, diabetes, antifungals
,
broad-spectrum antibiotic and central venous cathetersDifficult to identify with standard laboratory methodsLikely spread by contact with contaminated surfaces, equipment and person to person
Treatable with a
class of antifungal drugs called
echinocandins
Standard and Contact Precautions are recommended
Enhanced environmental cleaning using an EPA-registered disinfectant with fungal claimSlide73
Zika
Zika is spread mostly by the bite of an infected
Aedes
species. These mosquitoes bite during the day and night.Zika can be passed from a pregnant woman to her fetus. Infection during pregnancy can cause certain birth defects.There is no vaccine or medicine for Zika.
Local mosquito-borne Zika virus transmission has been reported in the continental United States. Slide74
Zika
Many people infected with Zika virus won’t have symptoms or will only have mild symptoms. The most common symptoms of Zika are
Fever
RashHeadacheJoint painConjunctivitis (red eyes)Muscle painSlide75
Summary
Preventing the transmission of infection is everyone’s responsibility and nurses have an impactful role in promoting and modeling best infection control
practices.
Disease transmission can be prevented by
consistently
using infection control
strategies.
New disease threats require increased vigilance by everyone
involved
in caring for
patients
.