PPT-Hemoglobin A1c Targets for Glycemic Controls

National Center for Health in Public Housing Clinical Quality Working Group Diabetes in PHPC Settings HBA1cgt9 in PHPC Settings American Diabetes Associations Press Release The ADA has long recommended that treatment goals be individualized based on factors both modifiable and nonmodifiable such as age life expectancy duration of disease resources and support and comorbid conditions The ADA recommends that a reasonable A1C goal for many nonpregnant adults with type 2 diabetes is less than 7 percent based on the available evidence to date from the ACCORD ADVANCE VADT and UKPDS international clinical trials which were evaluated and incorporated into ADAs Standards of Care . Monitoring for Glycemic Control. Chapter 9. Lori Berard, Ian Blumer, Robyn Houlden, David Miller, Vincent Woo. Key Messages. Glycated hemoglobin (. A1C. ) .  . measure every 3 months . (6 months if stable at target). b. d. g. a. a. Chromosome 16. Chromosome 11. 25%. 25%. a. a. b. d. g. 25%. 25%. 48%. 48%. 1.5%. 0.5%. 1.5%. 0.5%. Hemoglobin synthesis. a. a. a. a. a. a. b. g. d. b. d. g. HbA. HbF. HbA. 2. 98%. ~1%. Electrophoresis. Electrophoresis. Electrophoresis is a means of separating hemoglobin's. . . It depends on the migration of the hemoglobin molecules dissolved in a buffer on, or in, a supporting medium when an electric current is passed through them.. Glimepiride, Metformin & . Voglibose. Combination in T2DM. Dr. Mohammed Riyaz . M.D (Medicine), Masters . in . Endocrinology(UK). Chief . Endocrinologist. & Medical Director (EDSC). Type 2 diabetes population requiring stringent . By Louann W. Lawrence, Larry A. Broussard . Introduction. Porphyrins, hemoglobin, & myoglobin all contain porphyrin ring: 4 pyrrole groups bonded by methene bridges.. Porphyrins can chelate metals . Learning Objectives. ▪ . Different . Hemoglobin . variants. ▪ . Characteristics of . Hemoglobin . variants and . Hb. ▪. Different . Hemoglobin . combinations. Hemoglobin . V. ariants. There . must be . OBJECTIVES. Describe the . structure . of hemoglobin molecule. Describe . synthesis . of hemoglobin in brief.. List the . functions. of hemoglobin.. Enlist . various types. of normal and abnormal hemoglobin’s.. . By – . Dr. Sunita Mittal. Learning Objectives. ▪. Iron metabolism . ▪. Hemoglobin catabolism (Fate of old RBCs) . ▪. Prehepatic. Jaundice. Iron . (Fe. +2. ) Metabolism. Iron is essential for . Svjetlana Kalanj Bognar (. svjetla. na.kalanj.bognar. @mef.hr. ). Myoglobin. . and. hemoglobin, . oxygen-binding. . proteins. evolutionary. . demands. . of. . multicellular. . organisms. . and. ® Every Healthcare Provider Should Know According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the hemoglobin A1C assay may be unreliable for diagnosing and moni HbA1cEstimated Average Glucose (EAG) %mg/dLMmol/L 7 (76-120)5.4 6126 (100-152)7.0 7154 (123-185)8.6 8183 (147-217)10.2 )11.8 10240 (1 1126 (217-314)14.1228 (240-347)16.5 TABLE 1:Estimated Average Gluc 471. Objectives. Quantitative determination of hemoglobin in a blood sample.. . Hemoglobin structure. Hemoglobin (. Hb. ) is a . porphyrin. –iron (II) . protien. in RBCs that transport oxygen from the lungs to the rest of the body and carbon dioxide back to the lungs.. Hb. ) have related, but different, roles in the body. Hemoglobin:. Found in red blood cells. Promotes diffusion of O. 2 . throughout the body (binds O. 2 . at lungs,. . releases at tissues). Myoglobin:. . Nahid Kord, MD. NOV 27,2023. AGENDA. Introduction: . Background, Rating and Grading scale. Glucose: . Use/ Rationale: Diagnosis, Screening, Monitoring/ Prognosis. Analytical Considerations: Preanalytical, Analytical.