79 ved S neurona INTR cocystis neurona a parasite of the opossum Didelphis virginiana equine protozoal myeloencephalitis EPMThe pathogenesis of Sar infection in Sar host via the bloodstrea ID: 946965
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79 ved S. neurona. hematogenous method of distribution in thehost and an intracellular location by theparasite in a lymphocyte is suf
ficient toproduce clinical equine protozoal myeloen- INTR cocystis neurona , a parasite of the opos-sum ( Didelphis virginiana equine
protozoal myeloencephalitis (EPM).The pathogenesis of Sar infection in Sar host via the bloodstream.Alternatively,merogony occurs in
the endothelial cells oflood vessels of the host, in mononuclearcells, or in the vascular endothelium. merozoites that infect peripher
al with Culture-Derived neurona ozoites as a Model forEquine Protozoal Myeloencephalitis . Ellison, DVM, PhDEllis Greiner, PhD athog
enes, Inc., PO Box 970, Fairfield, FL 32634 b sity of Florida, Department of Pathobiology, Gainesville, FL 32611 c Kansas City, MO d K
EY cocystis neurona ELISA, equine protozoal myeloencephali- ABSTRA as designed to develop an experi- encephalitis in horses. neurona
an ataxic horse, was placed in continuousculture using bovine turbinate cells, and the S. neurona to infect lymphocytes. A horse that
wassubsequently experimentally infected with S. neurona phocytes developed encephalitis and ataxia. cocystis neurona spinal tissues o
f the infected horse by invitro culture. Three horses, each infectedwith a different number of merozoite-infected lymphocytes, were us
ed to esti-mate an infective dose of parasites neededeloencephalitis. This is the first reportof histologically confirmed experimental