at 6 months intention to treat 70 mm Hg in the renal denervation group vs 35 mm Hg in the sham group p 015 Mean change in 24hour blood pressure at 6 months treatment ID: 916003
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Slide1
Symplicity
Flex
Mean change in 24-hour blood pressure at 6 months (intention to treat): -7.0 mm Hg in the renal denervation group vs. -3.5 mm Hg in the sham group (p = 0.15)Mean change in 24-hour blood pressure at 6 months (treatment received): -8.3 mm Hg in the renal denervation group vs. -3.5 mm Hg in the sham group (p = 0.042)
Trial design: Participants with mild resistant hypertension were randomized to renal sympathetic denervation (Symplicity Flex catheter; n = 35) vs. sham procedure (n = 36).
Results
Conclusions
Among participants with mild resistant hypertension, renal denervation failed to reduce mean ambulatory blood pressure at 6 monthsAnalysis according to actual treatment received suggested a benefit from renal denervation
Presented by Dr. Steffen Desch at TCT 2014
(p
= 0.15)
Renal sympathetic denervation
-7.0
-3.5
Sham procedure
m
m Hg
Mean change in 24-hour blood pressure at 6 months