Proteoglycans are major components of connective tissue Networks of protein and carbohydrate interactions fix a cell to the extracellular matrix Some proteoglycans are components of cell membranes amp influence surface interactions ID: 910687
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Slide1
Proteoglycans are conjugates of proteins and glycosaminoglycans
Proteoglycans are major components of connective tissue
Slide2Networks of protein and carbohydrate inter-actions fix a cell to the extracellular matrix
Slide3Some proteoglycans are components of cell membranes & influence surface interactions
Slide4Glycoproteins (glycosylated proteins) are proteins with oligosaccharides attached
N
-linked to
Asn
(attached during synthesis)
O
-linked to
Ser
or
Thr
(attached after folding)
Slide5Diversity in the sequence of the attached sugar (microheterogeneity)
and in patterns of attachment to proteins (glycoforms)
Glycosylation adds great diversity to proteins
Slide6Glycosylations can influence protein structure
Slide7Glycolipids are usually found on the cell surface and are important in recognition
Slide8Glycoproteins and glycolipids are recognized and bound by
lectins
Slide9