PPT-Amino Acids, Peptides and Proteins

CHAPTER 3 Part 1 Amino Acids and Peptides To know the structure and naming of all 20 protein amino acids To know the structure and properties of peptides and the particularly the structure of the peptide bond. (Foundation Block). Dr. Ahmed Mujamammi. Dr. . Sumbul. . Fatma. Learning outcomes. What are the amino acids?. General structure.. Classification of amino acids.. Optical properties.. Amino acid configuration.. Peptide Bond. Amino acid residues in peptides and proteins are linked together through a covalent bond called the peptide bond.. Two amino acid molecules can be covalently joined through a substituted amide linkage, termed a . B.2. Properties of 2-amino acids . (B.2.2). Zwitterion. (dipolar) . amino acids contain both acidic and basic groups in the same molecule . therefore, are . amphoteric. in nature (capable of behaving as acids or bases). Unit objectives:. Identify amino acid classifications based on nutritional use and chemical properties of side chains. Describe the primary, secondary, tertiary and quaternary structures of proteins. amine group. Draw. a carboxylic acid group. Join. them together to form a molecule with an amine and . a carboxylic acid . group. Amino Acids. Building blocks of proteins. Two functional groups: a carboxylic acid and a primary amine. . are organic molecules that are the building block of . . proteins. .. -There is 20 . α. -amino acids commonly found in . proteins. . ( . they . have a carboxyl group and an amino group . . . Amino acids are weak . polyprotic. acids . . Neutral amino acids are (. gly. , ala, threonine ) are treated as diprotic acids .. acidic amino acids (. glu. , asp,) are treated as . triprotic. acids .. Each amino acid (aa) shares a common structure; i.e. an amine (NH. 2. ) group, an acid group (COOH), and a central carbon atom bonded to hydrogen and to a side chain (R).. The side chains qualify aas as acidic, basic, neutral, aromatic, and sulphur-containing amino acids.. Amino Acids are the building units of proteins.. The main role of amino acids is in the synthesis of structural and functional . proteins.. The . non-essential amino acids are either derived from the. Presented . by. Ms. . P. . . H. . Giri. Department of Microbiology. Deogiri . College, Aurangabad. B.Sc. F. Y.. Semester II. Paper No. V. Basic Biochemistry. Unit 3 Proteins. Ms. . Priyanka. H. . Giri.  . Amino . Acids are the building units of proteins. There are about 300 amino acids occur in nature. Only 20 of them enter in proteins synthesis..  . Structure of amino acids:. Four different . groups . u. sing paper chromatography. Kate Andrews. Lorraine Bruce. Unit 1 DNA and the Genome. 3 Control of gene expression. Separation and identification of amino acids using paper chromatography.. Cells and Proteins. A. . Peptides. are compounds, formed of less . than . 50 . amino acids . linked together by peptide bonds.. 1.. . Dipeptide. (2 amino acids and one peptide bond).. 2.. . Tripeptide. (3 amino acids and two peptide bonds).. BSc 3. rd. year . AMINO ACIDS. C. lassification of amino acids . Classification according to nature of side chain. PREPARATION OF AMINO ACIDS. 1. Gabriel Phthalimide synthesis. 2. Strecker’s synthesis.