PPT-Titration of weak acids Titration of amino acids

Amino acids are weak polyprotic acids Neutral amino acids are gly ala threonine are treated as diprotic acids acidic amino acids glu asp are treated as triprotic acids . What are amino acids?. Amino acids are the building blocks of proteins.. In the body, they exist as zwitterions.. Zwitterions can behave as both an acid or a base.. Today we will:. Study . the acid-base properties of amino acids, . Codons. Prefixes, Suffixes and Vocabulary. Poly. = many. Peptide bond . =bond between two amino acids.. Anti. = against, opposite. Dehydration. = loss of water. Polypeptide. = long assembled string of amino acids.. acetic acid, CH. 3. COOH, . pKa. = 4.8. 1.0. 0.8. 0.6. 0.2. 0.4. OH. -. equivalents. pH:. A. H. A. -. H. +. [A. -. ] . : [HA] = 1 : 1000. pH: . 1.8. = . pK. a. –3.0. Titration of a weak acid. acetic acid, CH. Stryer. Short Course. Chapter . 3. Amino Acid Structure. Alpha carbon. Sidechain. Proteins. peptides. Stereochemisty. L-amino acids. Glycine. R/S . vs. D/L. L-isoleucine. racemization. Ionization of Amino Acids. THE EXCRETION OF AMMONIUM IONS. A part of NH4+ that is formed in the degradation of amino acids is used for the biosynthesis of nitrogen compounds. In most of the land living vertebrates the excess NH4+ is converted in urea and in that form is excreted. In birds and reptiles it is converted into uric acid and in aquatic animals it is directly excreted as urea.. B.2. Properties of 2-amino acids . (B.2.2). Zwitterion. (dipolar) . amino acids contain both acidic and basic groups in the same molecule . therefore, are . amphoteric. in nature (capable of behaving as acids or bases). acetic acid, CH. 3. COOH, . pKa. = 4.8. 1.0. 0.8. 0.6. 0.2. 0.4. OH. -. equivalents. pH:. A. H. A. -. H. +. [A. -. ] . : [HA] = 1 : 1000. pH: . 1.8. = . pK. a. –3.0. Titration of a weak acid. acetic acid, CH. 18. /2014. Biochemistry I. Dr. Loren Williams. Proteinogenic Amino Acids. An amino acid contains . an amine group . a carboxylic acid group, . a side-chain (or R-group,. all attached to the same chiral carbon atom (the Cα). Part 1 - Amino Acids. Structure and Chemistry. Building Blocks of Proteins. Essential Amino Acids. Basic Structure. Stereochemistry. Side Chain Chemistry. Properties. Ionization. Bonding. Amino Acids & Proteins. . are organic molecules that are the building block of . . proteins. .. -There is 20 . α. -amino acids commonly found in . proteins. . ( . they . have a carboxyl group and an amino group . . . Peptide bond formation. : . α-carboxyl group of one amino acid (with side chain R1) forms a covalent peptide bond with α-amino group of another amino acid . ( . with the side chain R2) by removal of a molecule of water. The result is : Dipeptide ( i.e. Two amino acids linked by one peptide bond). By the same way, the dipeptide can then forms a second peptide bond with a third amino acid (with side chain R3) to give . backbone.  . atoms . (see aminoAcids1).  but a unique set of . side chain . atoms. It's the side chains that make the 20 amino acids different from each other. . 1. Use the three identical backbone pieces and three unique side chain pieces below to construct three amino acids in the space to the right.. Chapter 14. Section 1 – Properties of Acids and Bases. Section 2 – Acid Base Theories. Section 3 – Acid Base Reactions. 14.1 Properties of Acids and Bases. List. five general properties of aqueous acids and bases.. BSc 3. rd. year . AMINO ACIDS. C. lassification of amino acids . Classification according to nature of side chain. PREPARATION OF AMINO ACIDS. 1. Gabriel Phthalimide synthesis. 2. Strecker’s synthesis.