Cost-effectiveness of
60K - views

Cost-effectiveness of

chest x-ray . for facility-based systematic screening of tuberculosis among Ugandan adults. Presented by Achilles Katamba . O. n behalf . Matthew Murray, . Adithya. . Cattamanchi. , Claudia . Denkinger.

Download Presentation

Cost-effectiveness of




Download Presentation - The PPT/PDF document "Cost-effectiveness of" is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.



Presentation on theme: "Cost-effectiveness of"— Presentation transcript:

Slide1

Cost-effectiveness of chest x-ray for facility-based systematic screening of tuberculosis among Ugandan adults

Presented by Achilles Katamba On behalf Matthew Murray, Adithya Cattamanchi, Claudia Denkinger, Sandra Kik, Anja van’t Hoog, Madhukar Pai, David Dowdy

www.tb-mac.org

Slide2

Outline of Presentation

Introduction

What is cost-effectiveness analysis

Chest-x-ray as a triage test

What is

facility-based

systematic screening

?

Cost-effectiveness methods

Results

Sensitivity Analysis

Limitations

Implications

Slide3

Introduction

TB is the #1 infectious cause of death (as of 2015)

1/3 of TB patients are missed (by passive detection)

Systematic screening has many advantages

How should we find these missing

three million

?

Slide4

What is cost-effectiveness?

Slide5

Cost-effectiveness of

chest x-ray

for facility-based systematic screening of tuberculosis among Ugandan adults

Slide6

Slide7

Slide8

Cost-effectiveness of

chest x-ray

for

facility-based systematic screening

of tuberculosis among Ugandan adults

Slide9

What is facility-based systematic screening?

Slide10

What is facility-based systematic screening?

Slide11

Cost-effectiveness of

chest x-ray

for facility-based systematic screening of tuberculosis among Ugandan adults

Slide12

Cost- Effectiveness Methods

Slide13

Parameter Types

:

1) Probabilities

2) Diagnostic

3) Cost

4) Effectiveness

Slide14

Parameter Types:

1) Probabilities2) Diagnostic3) Cost4) Effectiveness

5%

95%

Slide15

Parameter Types:

1) Probabilities2) Diagnostic3) Cost4) Effectiveness

89%

11%

Slide16

Parameter Types:

1) Probabilities2) Diagnostic3) Cost4) Effectiveness

$24

$0

Slide17

Parameter Types:

1) Probabilities2) Diagnostic3) Cost4) Effectiveness

Cured

Died

Slide18

What was

the result

?

Slide19

What was the result?

Chest x-ray:

$

610

per YLG

Slide20

Chest x-ray: $610 ($200 - $1859) per YLG

*Assuming all model parameters are correct

What was

the result

?

Slide21

Sensitivity Analysis

Slide22

Sensitivity Analysis

Slide23

Sensitivity Analysis

Slide24

3-Way Sensitivity Analysis When Triage Test =$1

Slide25

3-Way Sensitivity Analysis When Triage Test =$3

Slide26

3-Way Sensitivity Analysis When Triage Test =$5

Slide27

3-Way Sensitivity Analysis When Triage Test =$10

Slide28

Limitations

Isolated to TB diagnosis and treatment

Future transmissions prevented unaccounted for

Cost-effectiveness by “international standard”

Use of YLG instead of DALYs

Slide29

Implications

CXR

is highly cost-effective for TB screening

Can extrapolate to similar settings

Scale-up can help detect missing 1/3 TB patients

R&D should focus on even better triage tests

Slide30

Thank you!

Dr. Dowdy, Dr.

Cattamanchi

, Dr.

Denkinger

, Dr.

Kik

, Dr.

van’t

Hoog

, Dr.

Pai

Dr. Bass, Dr. Friedman

Slide31

Thank you for listening

Questions/Comments